Obesity

High-fat diets interrupt stomach’s signals to the brain

the nerves in the stomach which signal fullness to the brain appeared to be desensitised after long-term consumption of a high-fat diet.

Indulging in fatty foods could destroy stomach’s signals to the brain, according to a new study which gives insight why many dieters tend to regain the weight after losing it.

New University of Adelaide research has found the nerves in the stomach which signal fullness to the brain appeared to be desensitised after long-term consumption of a high-fat diet.

The findings could explain why many dieters tend to regain the weight they have lost.

PhD student Stephen Kentish investigated the impact of high-fat diets on the ability of the gut to signal its fullness, and whether those changes revert back to normal by losing weight.

Study leader Associate Professor Amanda Page said laboratory studies showed the stomach’s nerve response does not return to normal upon a return to a normal diet.

“This means you would need to eat more food before you felt the same degree of fullness as a healthy individual,” she said.

“A hormone in the body, leptin, known to regulate food intake, can also change the sensitivity of the nerves in the stomach that signal fullness.

“In normal conditions, leptin acts to stop food intake. However, in the stomach in high-fat diet induced obesity, leptin further desensitises the nerves that detect fullness.”

Associate Professor Page said the two mechanisms combined meant that obese people needed to eat more to feel full, which fuels their obesity cycle.

She said the results had “very strong implications for obese people, those trying to lose weight, and those who are trying to maintain their weight loss”.

“Unfortunately, our results show that the nerves in the stomach remain desensitised to fullness after weight loss has been achieved,” she said.

Associate Professor Page says the researchers were not yet sure whether the effect was permanent or just long-lasting.

Source: Zee News

Education helps women from poor places beat obesity

A new study has suggested that educational status could help protect women living in socioeconomically disadvantaged areas fight obesity.

The new report’ authors said that income and education are frequently used as markers for studying health inequalities, although they are ‘conceptually distinct.’

They said that it’s possible that education is a marker of an individual’s access to health information, capacity to assimilate health-related messages, and ability to retain knowledge-related assets, like nutrition knowledge.

Lead author Lauren K. Williams, Ph.D., formerly of the Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences at Deakin University in Victoria, Australia, said that education is particularly important for women with low incomes who live in deprived areas.

She said that the research team mailed surveys to a large random sample of more than 4,000 women, ages 18 to 45, living in low-income towns and suburbs in Victoria. Women reported height, weight, education and personal income.

The authors said that women of amplified disadvantage, those living in disadvantaged neighbourhoods with both low education and personal income, may be at higher risk for high BMI.

 

Source: Zee news

 

Does changing breakfast habits really help you cut the flab?

It is a well documented fact that an association exists between breakfast and weight management, however a new study has found that previous researchers designed to find links between these two things often do not prove that one causes the other.

The research led by David Allison, Ph.D., associate dean for science in the University of Alabama School of Public Health, shows that the question of whether eating vs. skipping breakfast affects weight has not been answered by studies.

Andrew Brown, Ph.D., first author of the study, spearheaded the examination of 92 studies about the proposed effect of breakfast on obesity (PEBO). The PEBO-related research literature, the authors found, seemed to be influenced by factors that led to exaggerated beliefs and statements about the purported effects of breakfast consumption on obesity. These include research that lacks probative value and biased research reporting.

Allison and his team found that scientists collectively do not know as much about the relationship between skipping breakfast and obesity as previously thought, based on the current state of PEBO-related research.

Their meta-analysis indicated that there is certainty that breakfast-skipping and obesity are associated, but it cannot confirm whether there is a causal effect of skipping breakfast on obesity.

Brown said that although we know that breakfast-skippers are more likely to be overweight or obese, we do not know if making breakfast-skippers eat breakfast would decrease their weight, nor do we know if making breakfast-eaters stop eating breakfast would cause them to gain weight.

Meanwhile, Allison said that uncertainty should not be confused with evidence of no benefit or harm, though.

“It just means that right now we don’t know how changing breakfast-eating habits will influence obesity – eating versus skipping breakfast could help control weight, cause more weight gain or have no effect – and the effect may vary from person to person,” the researcher added.

The authors suggest that if causal claims are desired, different research on the topic is needed. They call for stronger study designs that include randomizing people to eat or skip breakfast to help determine causal effects of breakfast on obesity. UAB is leading such a trial in roughly 300 adults at five sites around the world; results from this study are expected in spring 2014.

The study is published in the American Journal of Clinical Nutrition.

 

Obesity tied to semi-frequent migraines

everyone should be aware that obesity is associated with an increased risk of episodic migraine and not wait until a patient has chronic migraine

Overweight and obese people are at higher-than-average risk of migraines, suggests a new study.

Researchers looking at so-called episodic migraines – headaches that occur less than every other day – found they were almost twice as common among obese people as among normal-weight adults.

“This suggests patients and doctors need to be aware that obesity is associated with an increased risk of episodic migraine and not wait until a patient has chronic migraine to address healthy lifestyle choices, such as diet and exercise, and to choose medications that impact weight with care,” lead researcher Dr. Lee Peterlin, from Johns Hopkins University School of Medicine in Baltimore, told Reuters Health in an email.

However, the researchers couldn’t be sure which came first – the extra weight or the headaches. And one migraine researcher not involved in the study said he would be cautious interpreting its findings.

“If this helps of course to make people believe they should lose weight, that’s great, but does it mean that reduction in weight will reduce migraine attacks, or treat migraines? That’s a question they haven’t addressed,” Dr. Tobias Kurth, of the French national research institute INSERM and the University of Bordeaux, said.

About 10 to 15 percent of people have episodic migraines, according to Peterlin.

Previous studies have linked obesity to chronic migraines, which by definition occur at least every other day. But there’s less evidence on whether weight also plays a role in less frequent migraines, researchers said.

To try to answer that question, Peterlin and her colleagues analyzed data on 3,862 people who participated in a national U.S. survey in the early 2000s, including 188 who reported having migraines an average of three or four times each month.

About 32 percent of people with episodic migraines were obese, based on their self-reported height and weight, compared to 26 percent of non-migraine sufferers.

After accounting for other differences between people with and without migraines, such as their age and smoking rates, the researchers found that being obese was linked to an 81 percent higher chance of having episodic migraines, they reported Wednesday in Neurology.

The obesity-migraine link was stronger among women and people under 50 years old but less clear for men and older adults, who have lower migraine rates in general.

Peterlin said there are a few possible explanations for the association, including that the same systems in the body that are activated during a migraine help regulate how much people eat. Also, people who get regular migraines may be less active because of the pain or take medications that influence weight gain, she said.

Kurth, who wasn’t involved in the new study, agreed lifestyle factors may play a role in both obesity and migraines. But he cautioned against drawing a direct link between weight and episodic migraines in the absence of more research.

“I’m just very careful, because I’m missing the big picture,” he told Reuters Health.

“If obesity would cause migraine, which is the suggestion of this study, we would expect to see an increase … in the prevalence of migraine, because we have such an epidemic of obesity in the United States,” he said. “And this is just not true.”

However, Peterlin said, rates of the two conditions wouldn’t necessarily be expected to go hand and hand on a larger scale – and that some studies have suggested episodic migraines are in fact becoming more common.

Source: fox news

 

15% of common strokes occur in adolescents and young adults

A team of researcher including an Indian origin has suggested that 15 percent of the most common type of strokes occur in adolescents and young adults, and more young people are showing risk factors for such strokes.

Co-author neurologist Jose Biller of Loyola University Medical Center said that the impact of strokes in this age group is devastating to the adolescent or young adult, their families and society.

About 85 percent of all strokes are ischemic, meaning they are caused by blockages that block blood flow to the brain. And more young people have risk factors for ischemic strokes.

Those risks include high blood pressure, diabetes, obesity, abnormal cholesterol levels, congenital heart disease and smoking.

Strokes in young people have a disproportionally large economic impact, because they can disable patients before their most productive years. And while coping with the shock of having a stroke, “younger survivors may be dealing with relationships, careers and raising children – issues that require additional awareness and resources,” the consensus report said.

Biller, one of the nation’s leading experts on stroke in young people, is second author of the consensus report. Biller is chair of the Department of Neurology of Loyola University Chicago Stritch School of Medicine. First author of the report is Aneesh Singhal, MD of Massachusetts General Hospital.

The study has been published in the journal Neurology.