Cancer

Colon cancer rates declining in older Americans

Colon cancer incidence rates have dropped 30 percent in the U.S. in the last 10 years among adults 50 and older due to the widespread uptake of colonoscopy, with the largest decrease in people over age 65. Colonoscopy use has almost tripled among adults ages 50 to 75, from 19 percent in 2000 to 55 percent in 2010.

The findings come from Colorectal Cancer Statistics, 2014, published in the March/April issue of CA: A Cancer Journal for Clinicians. The article and its companion report, Colorectal Cancer Facts & Figures, were released today by American Cancer Society researchers as part of a new initiative by the National Colorectal Cancer Roundtable to increase screening rates to 80 percent by 2018.

Colorectal cancer, commonly called colon cancer, is the third most common cancer and the third leading cause of cancer death in men and women in the United States. Its slow growth from precancerous polyp to invasive cancer provides a rare opportunity to prevent cancer through the detection and removal of precancerous growths. Screening also allows early detection of cancer, when treatment is more successful. As a result, screening reduces colorectal cancer mortality both by decreasing the incidence of disease and by increasing the likelihood of survival.

Using incidence data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) program and the Centers for Disease Control and Prevention’s National Program of Cancer Registries, as provided by the North American Association of Central Cancer Registries (NAACCR), researchers led by Rebecca Siegel, MPH found that during the most recent decade of data (2001 to 2010), overall incidence rates decreased by an average of 3.4 percent per year. However, trends vary substantially by age. Rates declined by 3.9 percent per year among adults aged 50 years and older, but increased by 1.1 percent per year among men and women younger than 50. That increase was confined to tumors in the distal colon and rectum, patterns for which a rise in obesity and emergence of unfavorable dietary patterns has been implicated.

Most strikingly, the rate of decline has surged among those 65 and older, with the decline accelerating from 3.6 percent per year during 2001-2008 to 7.2 percent per year during 2008-2010. The “larger declines among Medicare-eligible seniors likely reflect higher rates of screening because of universal insurance coverage,” the authors write. “In 2010, 55 percent of adults aged 50 to 64 years reported having undergone a recent colorectal cancer screening test, compared with 64 percent of those aged 65 years and older.”

Like incidence, mortality rates have also declined most rapidly within the past decade. From 2001 to 2010, rates decreased by approximately 3 percent per year in both men and women, compared with declines of approximately 2 percent per year during the 1990s.

“These continuing drops in incidence and mortality show the lifesaving potential of colon cancer screening; a potential that an estimated 23 million Americans between ages 50 and 75 are not benefiting from because they are not up to date on screening,” said Richard C. Wender, M.D., American Cancer Society chief cancer control officer. “Sustaining this hopeful trend will require concrete efforts to make sure all patients, particularly those who are economically disenfranchised, have access to screening and to the best care available.”

The data is being released at the launch of a nationwide effort to increase colorectal cancer screening rates to 80% by 2018. Public health leaders, including Assistant Secretary for Health Howard Koh, MD, MPH and American Cancer Society CEO, John R. Seffrin, PhD will join dozens of members of the National Colorectal Cancer Roundtable (NCCRT) at the National Press Club in Washington, D.C. on March 17th at 1:00 PM EDT. The NCCRT, an organization co-founded by the American Cancer Society and the U. S. Centers for Disease Control and Prevention, will focus on dramatically increasing colorectal cancer screening rates in the U.S. over the next four years, and increasing awareness of the potential for early detection and prevention of this cancer.

Source: Science daily

Illegal Ripening of Fruits Exposes Millions of Kenyans to Cancer

Dr. Mahesh Zagade, Food Commissioner, Maharashtra state, Food and Drug Administration, India

In an investigation in Kenya and India, writer Kiprotich Koros, discovers how corrupt businessmen use cancer-causing chemicals to ripen fruits. Officials now warn millions of people risk early grave by eating fruits laced with these chemicals.

An investigations in the past one month has unearthed rampant use of calcium carbide – an artificial ripening agent – by unscrupulous traders and supermarkets in Nairobi and Mombasa.

The chemical is used to hasten ripening of bananas, mangoes and apples for sale to millions of Kenyans. The chemical uniformly ripens fruits making them desirable to customers.

Samples taken from three leading supermarkets and groceries in Nairobi and Mombasa tested positive for the poisonous chemical used for welding and for making plastics.

Wholesale traders in big fruit markets in Gikomba, Nairobi, Marikiti and Kongowea in Mombasa are using the chemical secretly.

Fruit adulterated with calcium carbide may also be finding their way to Kenya from other parts of the world as there are no laws governing its use. The Pesticide Product Control Board (PPCB), Kenya Bureau of Standards (KEBS), Government Chemist and Kenya Agricultural Research Institute (KARI) are unable to test for the chemical as they did not have the necessary equipment or protocols.

Despite the serious health risks it poses, it is not listed by the Pesticides Control Products Board (PCPB) as a banned substance.

Some of the mangoes, bananas, oranges and apples in the Kenyan market are imported from Tanzania, Uganda, South Africa, Egypt and as a far as India where calcium carbide use is rampant.

This raises major public health concerns with the steep rise of cancer cases in the country over the past few years.

Cancer is the third killer disease in Kenya. According to the Nairobi Cancer Registry, 38,544 new cancer cases were diagnosed in 2012 with 26,941 deaths occuring in the same year.

Source: All Africa

Exercise advised for lymphoedema after breast cancer

Women who suffer swelling following breast cancer treatment should be encouraged to exercise, say experts.

New National Institute for Health and Care Excellence (NICE) guidance says exercise will not make the problem worse and could improve well-being.

One in five people treated for breast cancer will go on to develop lymphoedema in their arm, hand, fingers or chest.

It is a long-term condition that can lead to pain and loss of mobility.

The new NICE guidance, which is subject to consultation, says doctors and nurses should discuss with patients how exercise may improve their quality of life.

They should also stress that the current evidence shows “exercise does not prevent, cause or worsen lymphoedema”.

Clearing ‘confusion’
Many people with breast cancer go on to develop lymphoedema in their arm or chest following surgical or radiotherapy treatment.

It occurs when the body’s lymphatic system becomes damaged and is unable to drain fluid in the normal way.

Prof Mark Baker, director of the NICE centre for clinical practice, said: “For breast cancer patients, lymphoedema may occur as a result of treatment – such as surgery or radiotherapy – or cancer cells blocking the lymph system.

“Some people may be cautious of taking up exercise as they may think it could make their lymphoedema worse or bring it about in the first place.

“Our proposed new recommendations should clear up any confusion relating to the role that exercise can play for people with or at risk of this condition.”

Jackie Harris, clinical nurse specialist at Breast Cancer Care, said lymphoedema can severely restrict movement and impact lives.

“Lymphoedema can be controlled but will never go away and we know that regular exercise has many benefits for those living with or at risk of lymphoedema,” she said.

“Regular movement in everyday life or work can help keep joints supple and aids lymph drainage and extra exercises can also be useful if swelling restricts movement of the arm.”

Source; BBC news

Healthy ways to prevent cancer in teens!

CDC’s Division of Cancer Prevention and Control sponsored a supplemental issueExternal Web Site Icon of the Journal of Adolescent Health about ways to prevent cancer, with a focus on youth. The authors are experts from many different professions, showing the importance of working together to protect youth from cancer.

Youth go through many physical and social changes as they grow into adults. These changes create unique opportunities for cancer prevention. By addressing certain exposures and behaviors among today’s youth, we can reduce their chances of getting cancer in the future.

Examples include—

Promoting protective behaviors.

  • Completing the three-dose human papillomavirus (HPV) vaccine series.
  • Eating healthy food.
  • Getting enough physical activity.

Reducing harmful exposures.

  • Avoiding sunbathing and indoor tanning bed use.
  • Quitting smoking and other tobacco use.
  • Limiting alcohol use.
  • Avoiding exposure to certain chemicals.
  • Limiting radiation dose during medical imaging procedures.

Source: CDC

Surgery May Be Best for Young Men With Prostate Cancer

Younger men who have been diagnosed with prostate cancer may do well to consider surgery over so-called “watchful waiting,” a new study shows.

The new research,in the New England Journal of Medicine, is unlikely to end the long-running debate in the medical community over if and when surgery to remove the prostate is needed — particularly since the men in the study were diagnosed before the sensitive prostate-specific antigen (PSA) test was widely implemented to detect prostate cancer in its early stages.

The findings are the latest to come out of a 23-year-long, ongoing study comparing radical prostatectomy versus watchful waiting in 695 men who had been diagnosed with localized prostate cancer.

Between 1989 and 1999, researchers randomly assigned these men to either receive prostatectomy or not. The study found that those younger than 65 who underwent surgery to remove their prostates had a 15.8 percent lower risk of dying from prostate cancer than patients who had not had surgery. They also had a 25.5 percent lower risk of dying from any cause, as well as a 15.8 percent lower risk of the disease having spreading to other organs.

“Our results suggest that surgery may be more beneficial to younger men,” said study author Jennifer Rider, assistant professor of epidemiology at the Harvard University School of Public Health. Rider added that the men under 65 who had their prostates removed were also less likely to need radiation or chemotherapy.

The trial, funded by the Swedish Cancer Society and the U.S. National Institutes of Health, is the first of its kind to entail such an extended follow-up.
Urologists not involved with the research said the findings were important, particularly at a time when many men have concerns about the side effects of going under the knife for prostate cancer.

“This study makes a world of a difference,” said Dr. David B. Samadi, chairman of urology at Lenox Hill Hospital in New York City.
Samadi added that in the years since the study began, the operations to remove the prostate have become more refined.

“Surgery has become much improved,” he said. “ We’ve come a long way.”
“The important finding is that the benefits of surgery have increased over the course of time,” said Dr. Philip Kantoff, director of genitourinary oncology at Dana-Farber Cancer Institute in Boston.

But Dr. Otis Brawley, chief medical officer for the American Cancer Society, said that the results should be interpreted with caution, particularly since the study dealt with men who were not diagnosed using a PSA test – currently the common early detection method used in the U.S.

“That is a very different population from men in the U.S., where PSA screening means most cancers are caught at a much earlier stage,” he said in a statement to ABC News. The concern is that using prostate-removing surgery to treat these very early cancers may not be the best option, as it could mean a drastic surgery to remove a prostate that would never have presented a life-threatening problem.

And Dr. Lee Green, professor of family medicine at the University of Michigan, said more research will be needed before men facing a prostate cancer diagnosis get definite answers to the questions they have.

“It doesn’t prove that radical prostatectomy is better than less radical procedures, and it doesn’t prove that surgery is better than chemotherapy,” Green said. “It just says that surgery is better than doing nothing.”

Source; abc news

More Body Fat Raises Ovarian Cancer Risk, Study Suggests

The more a woman weighs, the greater her risk of ovarian cancer, a new report suggests.

It adds to strong suspicions that weight is somehow linked to ovarian cancer, one of the deadliest cancers and one that kills 14,000 U.S. women every year. And it adds ovarian cancer to a list of cancers affected by obesity or body fat, including breast cancer, colon cancer, endometrial cancer, kidney cancer and pancreatic cancer.

There’s also a link with height, although it’s not as strong as the evidence showing that weight, especially body fat, raises the risk, the American Institute for Cancer Research reports.

A team at the AICR looked at 25 studies with data on 4 million women, 16,000 of whom developed ovarian cancer.

“Greater body fatness is a probable cause of ovarian cancer in women,” the report concludes.

“This is an important finding because it shows a way for women to reduce their chances of getting ovarian cancer,” said Dr. Elisa Bandera of the Rutgers Cancer Institute of New Jersey, who helped write the study. “There is so much we don’t know about preventing ovarian cancer, but now we can tell women that keeping to a healthy weight can help protect against this deadly disease.”

Both the American Cancer Society and the National Cancer Institute list obesity as a suspected cause of ovarian cancer.

But the AICR report suggests that a woman doesn’t have to be obese — with a BMI of 30 or greater — for the risk to start growing. Even overweight women have a higher risk, the data suggests, starting at a BMI of about 28, which is considered overweight but not quite obese. (There’s a BMI calculator here).

There are many reasons why fat may raise cancer risk. Fat cells secrete estrogen, a hormone that can help fuel cancer, and people who are overweight or obese have overall higher levels of inflammation, which can affect heart disease and cancer risk alike. Fat cells produce other hormones, such as leptin and growth factors, that may affect the out-of-control cell growth that underlies cancer.

It’s also possible that something else is driving both body growth and cancer — perhaps a genetic cause.

The AICR report looked for evidence of other causes of ovarian cancer but could not find enough evidence to implicate any specific foods such as eggs, milk, coffee, tea, meat, fats or vitamins.

Source: NBC news

Oh Baby: Giving Birth 10 Times May Reduce Mom’s Cancer Risk

Women who give birth to 10 or more children may have a reduced risk of cancer, a new study from Finland suggests. Researchers examined cancer risk in nearly 5,000 Finish women who gave birth at least 10 times before 2010.

Over a three-decade period, there were 656 cases of cancer in these women, about 200 fewer cases than would be expected based on cancer rates in the general Finnish population, the study found.

In fact, the rate of new cancer cases was 24 percent lower among women who delivered 10 or more babies compared to those in the general population, the researchers said.
This overall reduction in cancer risk came mainly from decreased rates of breast cancer and gynecological cancers, including ovarian and endometrial cancer (cancer of the uterus lining). For these cancers, the rate of new cancer cases was about 50 percent lower in women with 10 or more deliveries, compared to the general population.

The researchers aren’t sure whether the findings apply to women who have just one, two or three children, but plan to conduct another study to find out, said study researcher Dr. Juha Tapanainen, of the Department of Obstetrics and Gynecology at Helsinki University Central Hospital.
Pregnancy and cancer risk

In the study, women who had 10 or more babies were about five years younger when they gave birth to their first child, compared to average Finnish women. It’s known that becoming pregnant at a young age helps protect against breast cancer, Tapanainen said.
Women who give birth before age 20 have about half the risk of breast cancer as those who give birth for the first time after age 30, according to the National Institutes of Health. Some researchers hypothesize that this is because pregnancy speeds up the process of breast cell maturation, and that mature cells are more resistant to cancer, Tapanainen said. So, women who have children at younger ages develop mature, cancer-resistant breast cells sooner.

Previous studies have also found that giving birth to at least five children reduces the risk of breast cancer. This may be because pregnancy halts the menstrual cycle, so the breast cells of women who have many pregnancies are exposed to less estrogen, according to the American Cancer Society. (Exposure to estrogen is thought to increase the risk of breast cancer.)

The halting of ovulation, and the hormone changes that period in life causes, may also play a role in the reduced risk of ovarian and endometrial cancers.
Many women in the new study who had 10 or more children were members of the Laestadian movement, which is part of the Lutheran Church in Finland, the researchers said. Women in this group are similar to average Finnish women in terms of their lifestyle, but their religion prohibits the use of contraceptives.

Studies on the effect of hormonal contraceptives on cancer risk have been inconclusive, but some studies suggest that the contraceptives reduce the risk of ovarian and endometrial cancer. Thus, it’s possible that if Laestadian women in the study also took contraceptives, and still had multiple pregnancies, it would even further reduce their risk of these cancers, Tapanainen said.

Risks of many pregnancies

The study further linked having 10 babies with a reduced risk of basal cell skin cancer, and an increased risk of thyroid cancer. But the researchers don’t know the reason for this link.

Researchers noted that women who are able to have 10 or more children are likely healthier than women in the general population. But this factor alone is unlikely to explain the link between having 10 babies and the reduced risk of these cancers, Tapanainen said.

In general, the findings suggest that having more children doesn’t result in an increased occurrence of cancer, Tapanainen said. The protective effect is seen after five births, and is even greater with 10 births, Tapanainen said.
Despite the reduced risk of cancer, giving birth to five or more children does come with its own dangers, increasing the risk of pregnancy complications, such as premature birth and hemorrhaging after delivery.

Source: Yahoo news

Skin cancer may up risk of other cancers

People who have had common skin cancers may be at an increased risk of developing melanoma and 29 other cancer types, a new study has warned. Individuals who had nonmelanoma skin cancer (NMSC) were at increased risk for subsequently developing other cancer types, and this association was much higher for those under 25 years of age, researchers said.

NMSC is the most common type of skin cancer. It is relatively easy to treat if detected early, and rarely spreads to other organs, they said. “Our study shows that NMSC susceptibility is an important indicator of susceptibility to malignant tumours and that the risk is especially high among people who develop NMSC at a young age,” said Rodney Sinclair, professor of medicine at the University of Melbourne in Australia.

“The risk increases for a large group of seemingly unrelated cancers; however, the greatest risk relates to other cancers induced by sunlight, such as melanoma,” said Sinclair. Compared with people who did not have NMSC, those who did were 1.36 times more likely to subsequently develop any cancer, including melanoma and salivary gland, bone, and upper gastrointestinal cancers.

Survivors younger than 25 years of age, however, were 23 times more likely to develop any cancer other than NMSC. In particular, they were 94 and 93 times more likely to get melanoma and salivary gland cancer, respectively. “Our study identifies people who receive a diagnosis of NMSC at a young age as being at increased risk for cancer and, therefore, as a group who could benefit from screening for internal malignancy,” said Sinclair.

Researchers hypothesised that people who develop skin cancers later in life do so as a result of accumulated Sun exposure, while those who develop skin cancer at a younger age may do so as a result of an increased susceptibility to cancer in general. To investigate this, they stratified the risk ratios by age and discovered that young people with NMSC are more cancer-prone.

The researchers constructed two cohorts: one of 502,490 people with a history of NMSC, and a cohort of 8,787,513 people who served as controls. They followed up with the participants electronically for five to six years, and 67,148 from the NMSC cohort and 863,441 from the control group subsequently developed cancers.

They found that for those who had NMSC, the relative risk for developing cancers of the bladder, brain, breast, colon, liver, lung, pancreas, prostate, and stomach remained consistently elevated for the entire period of the study, and the risk for cancers of the brain, colon, and prostate increased with time.

The study was published in the journal Cancer Epidemiology, Bio-markers & Prevention.

Source: Indian Express

Young skin cancer survivors at higher risk of different cancers in the future

Young skin cancer survivors may not be completely in the clear, a recent study shows, with higher incidence of further cancers – including melanoma – developing in the future.

The findings of a newly-published large study mar successful remission of skin cancer survivors, as nonmelanoma survivors were found to be 1.36 times more likely to develop melanoma later in life. For patients under 25, the risk was boosted to 23 times more likely, but just 3.5 higher for survivors aged 25 to 44. The patients who developed nonmelanoma cancers prior to the of 25 bear the heaviest brunt, being 53 times more likely to develop bone cancer, a 26 times higher chance of developing blood cancers, and 20 times more likely to develop brain cancer. They are also faced with a higher risk of contracting any other type of cancer – around 14 times as likely – including breast, colon, liver, prostate, and stomach.

The study was completed by researchers at the University of Melbourne, Australia, and the University of Oxford, England. Observing 502,490 people who had previously had nonmelanoma cancers, as well as 8,787,513 people with no history of skin cancer, the study found that more than 13 percent of people in the first group went on to develop another cancer. In the second group, the number was around nine percent. However, researchers cautioned that the study considered both basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) together, without differentiating the two – thus unable to determine the precise chance of developing cancer in the future based on the type of cancer patients had in the past. “It might be that one type of NMSC [non-melanoma skin cancer] is more strongly associated with increased risks of subsequent primaries; however, only subtle differences have been noted in studies that do differentiate SCCs and BCCs,” the study read.

Nevertheless, the researchers recommended early screening as the best course of action. “Early detection of cancers through screening of asymptomatic people works best when screening can be targeted at those at greatest risk,” said study author Dr. Rodney Sinclair, M.B.B.S., M.D., the director of dermatology at the Epworth Hospital and professor of medicine at the University of Melbourne. “Our study identifies people who receive a diagnosis of NMSC [non-melanoma skin cancer] at a young age as being at increased risk for cancer and, therefore, as a group who could benefit from screening for internal malignancy.”

Source; Tech Times

Top 5 health benefits of mango juice

The king of fruits, Mango not only tastes good that but also offers a number of health benefits for your body. The tropical fruit is sweet in taste and is available in a wide variety. It is widely used in various cuisines like chutney, pickles, amras, lassi etc.

Mango juice contains vitamins and minerals essential for good health.

Here are five health benefits why you should indulge in this juicy fruit:

  • -Mango juice helps reduce the development of cancer cells within the body.
  • -It contains fiber which aids in digestion and elimination of acids.
  • -Mangoes are a rich source Vitamin A and flavonoids which help promote good eyesight and prevents night blindness and dry eyes.
  • -Mango juice helps regulate blood pressure as it contains potassium that assists your muscles, heart and nerves’ functions.
  • -In case of pregnancy, mango juice is very much beneficial to help increase the speed of the child’s physical and mental development as it is low in calories and rich in other essential nutrients.

Source: Zee news