Amino acid

Shun snacks that affect a good night’s sleep

Do some bedtime snacks help you sleep better? Perhaps not.

Several studies suggest that eating a small snack a few hours before bedtime may help you sleep by preventing hunger from waking you.

But are there snacks that guarantee you sleep?

Some people say that cereal with milk, peanut butter on toast, and cheese with crackers are good bedtime snacks because they combine carbohydrates with protein.

The theory is based on the fact that tryptophan, an amino acid, makes you sleepy.

A new research done on the sedating effects of tryptophan needed up to 15 grams of tryptophan to create an effect.

And you would need to eat more than a pound of turkey to get just one gram of tryptophan!

To get a good night’s sleep, it is more important to avoid foods like high-fat foods, garlic-flavoured and highly spiced foods, alcohol, caffeine and any beverages before bed, reported.

Other than foods, sticking to a regular bedtime and wake time schedule helps keep you in sync with your body’s circadian clock, a 24-hour internal rhythm affected by sunlight.

Try not to nap too much during the day – you might be less sleepy at night.

Exercise at regular times each day. Try to finish your workout at least three hours before bedtime, said the report.

Source: DNA India

New treatment for osteoporosis discovered

After more than four years of investigation, researchers from the Ageing Bone Research Program (Sydney Medical School’s Nepean campus), have found the treatment has shown very promising results in animal experiments.

The compound is called picolinic acid, a product derived of the essential amino acid tryptophan.

Lead researcher Professor Gustavo Duque said the odorless compound can be easily dissolved in water.

“This is a major step in the development of a completely new type of medication for osteoporosis. Instead of stopping bone destruction, our compound instead stimulates bone formation,” he said.

“The product is easily dissolved in water, has a higher level of absorption and did not induce any side effects in the treated mice.

“When this medication was administered in the water of normal and menopausal mice, picolinic acid strongly and safely increased bone mass in normal mice and rescued bone from menopause-associated osteoporosis.”

Professor Duque said the team had patented the compound and will expand their trials to humans in the near future in a bid to address the increasing numbers of people developing the condition.

“Osteoporosis affects an estimated 300 million people worldwide. One in three women over 50 will experience osteoporotic fractures, as will one in five men.

“Despite the current treatments available, by 2050, the worldwide incidence of hip fracture in men is projected to increase by 310 percent and 240 percent in women.

“This increase is explained by the low rate of diagnosis and treatment for osteoporosis, as well as some concerns about the potential side effects of the current treatments.

“There are also close similarities between the majority of the osteoporosis medications in terms of their anti-fracture effect and mechanism of action.”

According to Professor Duque, there is a reduction in bone formation as part of the ageing process that predisposes people to osteoporosis.

“In this case we are targeting the real problem by stimulating the bone forming cells to work and produce more bone, thus increasing bone mass and hopefully preventing new fractures,” he said.

Source: The University of Sydney