WHO

Polluted air linked to 7 million deaths in 2012: WHO

Air pollution killed about 7 million people in 2012, making it the world`s single biggest environmental health risk, the World Health Organisation (WHO) said on Tuesday.

The toll, a doubling of previous estimates, means one in eight of all global deaths in 2012 was linked to polluted air and shows how reducing pollution inside and outside of people`s homes could save millions of lives in future, the United Nations health agency said.

Air pollution deaths are most commonly from heart disease, strokes or chronic obstructive pulmonary disease. It is also linked to deaths from lung cancer and acute respiratory infections.

“The evidence signals the need for concerted action to clean up the air we all breathe,” said Maria Neira, head of the WHO`s environmental and social public health department.

“The risks from air pollution are now far greater than previously thought or understood, particularly for heart disease and strokes,” she said.

Poor and middle-income countries in southeast Asia and the Western Pacific region had the largest air pollution-related burden in 2012, with 3.3 million deaths linked to indoor air pollution and 2.6 million deaths to outdoor air pollution.

Indoor pollution is mostly caused by cooking over coal, wood and biomass stoves. The WHO estimates that around 2.9 billion people worldwide live in homes using wood, coal or dung as their primary cooking fuel.

Flavia Bustreo, a WHO family health expert, said women and children – especially those living in poor countries – often bear the brunt of the risks from indoor pollution “since they spend more time at home breathing in smoke and soot from leaky coal and wood cooking stoves.”

Outdoors, air is mainly polluted by transport, power generation, industrial and agricultural emissions and residential heating and cooking.

Research suggests outdoor air pollution exposure levels have risen significantly in some parts of the world, particularly in countries with large populations going through rapid industrialisation, such as China and India.

The WHO`s cancer research agency IARC published a report last year warning that the air we breathe is laced with cancer-causing substances and should be officially classified as carcinogenic to humans.

Carlos Dora, a WHO public health expert, called on governments and health agencies to act on the evidence and devise policies to reduce air pollution, which in turn would improve health and reduce humans` impact on climate change

“Excessive air pollution is often a by-product of unsustainable policies in sectors such as transport, energy, waste management and industry,” he said.

“In most cases, healthier strategies will also be more economical in the long term due to healthcare cost savings as well as climate gains.”

Source: Zee news

China Smog Is Economic, Regional Health Problem, WHO Chief Says

China’s air pollution is a regional health issue and impacts the economy in terms of foreign investment and talent retention, the United Nation’s health agency chief said.

“Talented people have actually talked to me, and they’ve changed their decision to settle in China because of the air pollution,” World Health Organization Director-General Margaret Chan said today in an interview with Bloomberg TV in Hong Kong. “I think Chinese authorities understand this and they know what’s going on.”

Chinese Premier Li Keqiang said earlier this month that pollution is a major problem and the government will “‘declare war’’ on smog by removing high-emission cars from the road and closing coal-fired furnaces. Air pollution led to genetic changes that may have sapped learning skills in children whose mothers were exposed to a Chinese coal-fired power plant a decade ago, researchers reported on March 19.

Pollution in Beijing today rose to more than 10 times levels considered safe by the World Health Organization. The concentration of PM2.5 — the small particles that pose the greatest risk to human health — hit 270 micrograms per cubic meter in the Chinese capital as of 12 p.m., a U.S. Embassy monitor said. The WHO recommends 24-hour exposure to PM2.5 levels of less than 25.

Smog produced by China affects not just the country, Chan said, as winds can carry pollutants across borders to neighboring states and even further afield. Pollution from China’s export manufacturers travels across the Pacific Ocean to the U.S. West Coast, contributing to smog in Los Angeles, according to a University of California, Irvine study published in January.

Source: bloomberg

Drug-resistant TB a “global health security risk,” WHO says

Half a million people fell sick with dangerous superbug strains of tuberculosis (TB) in 2012, but fewer than one in four were diagnosed, putting the rest at risk of dying due to the wrong medicines or no treatment at all.

Latest data from the World Health Organization (WHO), which says drug-resistant TB is a “global health security risk,” showed a third of the estimated 9 million people who contract TB in any form each year do not get the care they need.

This has led to drug resistance spreading around the world at an alarming rate and has given rise to incurable strains of the bacterial infection — known as totally drug-resistant TB — which cannot be treated with any known medicines.

“Earlier and faster diagnosis of all forms of TB is vital,” said WHO director general Margaret Chan as the U.N. health agency published new TB data on Thursday. “It improves the chances of people getting the right treatment and being cured, and it helps stop spread of drug-resistant disease.”

Last year the WHO called for multidrug-resistant tuberculosis (MDR-TB) to be recognized as a public health crisis. It says the contagious, deadly superbug forms of the disease carry “grave consequences for those affected.”

Treating even regular TB is a long process. Patients need to take a cocktail of antibiotics for six months and many fail to complete the treatment.

This in turn has fuelled the emergence of drug-resistant TB — a man-made problem that has grown in the past decade because people sick with regular TB were either being given the wrong medicines or wrong doses or did not complete their treatment.

Diagnosis gap

Experts say one of the major hurdles to tackling drug-resistant strains effectively is that so many patients who have contracted them do not know it and so continue with the wrong treatments or are not treated at all.

Some of the poorest and most ill-equipped countries have only one central laboratory, which often has limited capacity to diagnose MDR-TB. In other cases, patient samples have to be sent to other countries for testing.

Traditional diagnostic tests can take more than two months to get results, leaving a dangerous gap in which the patient is not getting the right treatment and is putting others at risk of catching the contagious disease.

The WHO says up to 2 million people worldwide may be infected with drug-resistant TB by 2015.

Newer, speedier diagnostic tests have been developed in recent years, but the problem has been getting the technology and know-how to the countries where they are needed most.

However, Chan cited encouraging signs from an international project known as EXPAND-TB (Expanding Access to New Diagnostics for TB), financed by UNITAID, which has helped to triple the number of MDR-TB cases diagnosed in participating countries.

In 2009, UNITAID backed the EXPAND project with $87 million US to new TB diagnostic technologies in 27 low- and middle-income countries, which together account for around 40 per cent of the global MDR-TB burden.

“The gap in access to TB diagnostics and care is far from filled, but it is narrowing,” said Mario Raviglione, director of WHO’s global TB program. “Increased capacity and reduced prices mean that we can reach more people.”

Source: cbc news

India still home to quarter of global TB cases

Despite having a strong public sector programme to contain the disease, tuberculosis still remains a cause of concern for India, which has nearly a quarter of the global burden of TB, health experts said.

Experts said measures which can help strengthen the fight against the disease include involvement of the private sector, more political commitment to create awareness and containing risk factors like malnutrition.

“TB is still a cause for concern. It is the sheer numbers in India and the associated problems like poverty which are responsible for this,” Soumya Swaminathan, director, National Institute for Research in Tuberculosis, an organization under the health ministry, told IANS.

According to the World Health Organization (WHO), there are 2.2 million tuberculosis patients in India, which makes it the world’s highest TB-burden country. TB killed 1.3 million people worldwide in 2012 and India alone accounted for 26 percent of the total cases.

She said that China and Brazil have done better in controlling TB in their respective countries and India needs to do more.

“In eight years, India has made tremendous progress as far as containing TB. But it needs to do much more,” she added.

But R. S. Gupta, deputy director general (TB) in the health and family welfare ministry, said: “Treatment success rates have been above 85 percent for several years in the country.”

Gupta told IANS that the overall quality of TB services, including human resources and systems for financial management are being strengthened.

To achieve the National Tuberculosis Programme’s (NTP) ambitious goal of universal health care access for all people with TB by 2017, financial commitments must be maintained by all partners, including international agencies, he said.

The state-run tuberculosis control initiative of the government, NTP provides free of cost, quality anti-tubercular drugs across the country. More than 1.5 million people avail the facility at 13,000 centres.

Gupta said that the private sector should be involved more as most patients are being treated in private clinics.

Agreed Swaminathan, who said that the government needs to work in tandem with the private sector.

“Standard procedures need to be followed for notification of the disease and diagnosis, especially by private practioners,” Swaminathan told IANS.

In 2012, India declared TB to be a notifiable disease. It means that with immediate effect all private doctors, caregivers and clinics treating a TB patient had to report every case to the government.

According to a recent WHO report, India has achieved the Millenium Development Goal (MDG) target for TB which says that the incidence of the disease should be falling. It is on track to reach the 2015 targets for reductions in TB prevalence and mortality.

But it added that India accounts for 31 percent of the estimated 2.9 million missed TB cases — people who were either not diagnosed or diagnosed but not reported to NTP.

It is estimated that about 40 percent of the Indian population is infected with TB bacteria, the vast majority of whom have latent rather than active TB.

Listing the other steps needed, Swaminathan said: “Getting more political commitment and activism from civil society to create awareness about TB like it was done in the case of HIV/AIDS would be a great help.”

India also needs to contain the risk factors associated with the disease. The biggest among them is malnutrition, which makes people more susceptible to the development of active TB. Tuberculosis patients have lower Body Mass Index (BMI), muscle mass and subcutaneous stores of fat.

“Malnutrition is the biggest risk factor and it has been overlooked,” she said, adding that the “disease needs to be fought on a common platform by all stakeholders.”

Source: Zee News

 

Poor diagnosis driving global multidrug-resistant TB, WHO warns

Half a million people fell sick with dangerous superbug strains of tuberculosis (TB) in 2012, but fewer than one in four were diagnosed, putting the rest at risk of dying due to the wrong medicines or no treatment at all.

Latest data from the World Health Organisation (WHO), which says drug-resistant TB is a “global health security risk”, showed a third of the estimated 9 million people who contract TB in any form each year do not get the care they need.

This has led to drug resistance spreading around the world at an alarming rate and has given rise to incurable strains of the bacterial infection – known as totally drug-resistant TB – which cannot be treated with any known medicines.

“Earlier and faster diagnosis of all forms of TB is vital,” said WHO director general Margaret Chan as the U.N. health agency published new TB data on Thursday. “It improves the chances of people getting the right treatment and being cured, and it helps stop spread of drug-resistant disease.”

Last year the WHO called for multidrug-resistant tuberculosis (MDR-TB) to be recognized as a public health crisis. It says the contagious, deadly superbug forms of the disease carry “grave consequences for those affected”.

Treating even regular TB is a long process. Patients need to take a cocktail of antibiotics for six months and many fail to complete the treatment.

This in turn has fuelled the emergence of drug-resistant TB – a man-made problem that has grown in the past decade because people sick with regular TB were either being given the wrong medicines or wrong doses or did not complete their treatment.

HURDLES

Experts say one of the major hurdles to tackling drug-resistant strains effectively is that so many patients who have contracted them do not know it and so continue with the wrong treatments or are not treated at all.

Some of the poorest and most ill-equipped countries have only one central laboratory, which often has limited capacity to diagnose MDR-TB. In other cases, patient samples have to be sent to other countries for testing.

Traditional diagnostic tests can take more than two months to get results, leaving a dangerous gap in which the patient is not getting the right treatment and is putting others at risk of catching the contagious disease.

The WHO says up to 2 million people worldwide may be infected with drug-resistant TB by 2015.

Newer, speedier diagnostic tests have been developed in recent years, but the problem has been getting the technology and know-how to the countries where they are needed most.

However, Chan cited encouraging signs from an international project known as EXPAND-TB (Expanding Access to New Diagnostics for TB), financed by UNITAID, which has helped to triple the number of MDR-TB cases diagnosed in participating countries.

In 2009, UNITAID backed the EXPAND project with $87 million to new TB diagnostic technologies in 27 low- and middle-income countries, which together account for around 40 percent of the global MDR-TB burden.

“The gap in access to TB diagnostics and care is far from filled, but it is narrowing,” said Mario Raviglione, director of WHO’s global TB program. “Increased capacity and reduced prices mean that we can reach more people.”

UNITAID was launched in 2006 by the governments of Britain, Brazil, Chile, France and Norway to give sustainable funding for the fight against HIV/AIDS, malaria and tuberculosis. About 70 percent of its funds come from a levy on airline tickets.

Source: Reuters

China ‘has halved its TB problem,’ survey data suggests

China has more than halved its tuberculosis (TB) prevalence, with rates falling from 170 to 59 per 100,000 population, figures suggest.

The Lancet report says the success is due to a huge expansion of a community-based disease control programme. The World Health Organization says other countries could use a similar approach.

China is a major contributor to the global TB pandemic, accounting for more than one-tenth of cases worldwide. The Lancet report reveals what progress China has made on reducing this burden, based on a 20-year-long analysis of national survey data.

Between 1990 and 2000, levels of TB were reduced in provinces where the WHO-recommended directly observed treatment, short-course (DOTS) programme – rapid detection and cure of infectious tuberculosis patients living in the community – was adopted.

By 2010, TB prevalence in China fell by 57%, tripling the reduction of the previous decade.

The increase of known TB cases treated using DOTS rose from 15% in 2000 to 66% in 2010.

Lead researcher Dr Yu Wang, from the Chinese Centre for Disease Control and Prevention in Beijing, said: “One of the key global TB targets set by the Stop TB Partnership aims to reduce tuberculosis prevalence by 50% between 1990 and 2015.

“This study in China is the first to show the feasibility of achieving such a target, and China achieved this five years earlier than the target date.”

The 2014 World Health Assembly will look at eliminating TB and setting ambitious new targets which could include a 50% reduction in tuberculosis prevalence between 2015 and 2025.

Giovanni Battista Migliori from WHO said: “The results from China show the feasibility of achieving such a target by aggressively scaling up the basic programmatic elements of tuberculosis control both within and outside the public sector.”

He said other countries could learn from China’s example.

TB remains a big issue in many countries, including India, Russia and many African nations. Better diagnostic tools and treatments are still needed.

Aaron Oxley of Stop TB UK said: “China has shown what is possible to achieve when attention and resources are brought to the fight against TB. But nearly 4,000 people still die from TB every day, and 3 million cases go undiagnosed each year. We still have a long way to go.”

Source: BBC news

WHO-proposed sugar recommendation comes to less than a soda per day

The World Health Organization wants you to stop eating so much sugar. Seriously. In draft guidelines proposed this week, WHO is encouraging people to consume less than 5% of their total daily calories from sugars. The organization’s current guidelines, published in 2002, recommend eating less than 10% of your total daily calories from sugars.

Most Americans still consume much more. Our sweet tooth increased 39% between 1950 and 2000, according to the USDA. The average American now consumes about three pounds of sugar each week. “There is increasing concern that consumption of free sugars, particularly in the form of sugar-sweetened beverages, may result in … an increase in total caloric intake, leading to an unhealthy diet, weight gain and increased risk of noncommunicable diseases,” WHO said in a statement.

Of particular concern, WHO said, is the role sugar plays in causing dental diseases worldwide. For an adult at a normal body mass index, or BMI, eating 5% would be around 25 grams of sugar — or six teaspoons. That’s less than is typically found in a single can of regular soda, which contains about 40 grams of sugar.

To find the amount of calories from sugar in a product, multiply the grams by 4. For example, a product containing 15 grams of sugar has 60 calories from sugar per serving, according to the American Heart Association. If you eat 2,000 calories a day, that’s 3%.

WHO’s proposed guidelines apply to sugars added to foods by manufacturers, as well as those found naturally in honey, syrups, fruit juices and fruit concentrates. They do not apply to those found in fresh produce.

“Much of the sugars consumed today are ‘hidden’ in processed foods that are not usually seen as sweets,” the WHO website states.

Did you know sugar is often added to your frozen pizza? How about your bread, soup, yogurt and mayonnaise? As consumers became more concerned about the amount of fat in their food, manufacturers went out of their way to make low-fat items — often substituting sugar to preserve the taste.

Choosing foods with fewer added sugars at the grocery story may soon get a little easier. The Food and Drug Administration has proposed several changes to the nutrition labels you see on packaged foods and beverages.

The proposed labels would also note how much added sugar is in a product. Right now, it’s hard to know what is naturally occurring sugar and what has been added by the manufacturer.

The WHO guidelines will be open for public comment until March 31. Then WHO will finalize and publish its recommendations.

Source: CNN news

Measles Outbreak Threatens Children’s Lives in Guinea

UNICEF and its partners have begun to organize a campaign to vaccinate over 1.6 million children to stop a measles outbreak in Guinea amid growing number of cases among children especially in the capital Conakry.

Since November last year, 37 cases have been confirmed in the capital-all children under 10 years old. Over the past few weeks, the number of cases of measles has been increasing sharply and led to the death of one child.

This recent spike has prompted the Ministry of Health and Public Hygiene of Guinea to officially declare an outbreak in the Conakry municipalities of Matam, Matoto, and Ratoma. The disease has also been reported in other parts of the country -namely the prefectures of Boké, Coyah, Dubreka, Kissidougou, and Mandiana.

“We are very concerned about this outbreak. Measles is highly contagious and extremely dangerous–especially for young, malnourished children. As we’ve already seen, it can be fatal. In a densely populated city like Conakry, disease spreads quickly,” said UNICEF Representative in Guinea Dr. Mohamed Ayoya.

The Government of Guinea, UNICEF, the World Health Organization (WHO) and Médecins Sans Frontières (MSF) are joining forces to set up coordinated mechanisms to contain the outbreak. For the initial response, UNICEF will provide vaccines, refrigerators, needles, and other medical supplies and logistical support to the Government for the vaccination of children in the Kaloum and Dixinn neighbourhoods of Conakry as well as in the affected areas outside the capital. MSF and WHO will support vaccination efforts in the outbreak-declared areas of Conakry -namely Matam, Matoto, and Ratoma.

The vaccination phase of the national campaign will begin in the coming weeks as soon as vaccines, supplies and funding to ensure a continuous rollout are available.

Additionally, UNICEF and its partners will supply the Government with medicine to treat those who have already been infected by measles.

“There is no time to waste,” said Felix Ackebo, UNICEF Deputy Representative. “We need to move faster than the disease. Because measles takes up to 12 days to reveal its symptoms, it is possible that the disease has spread further into the country. All children who are still not immunized are at risk. Therefore, an outbreak immunization campaign is required as soon as possible.”

UNICEF and its partners are urgently seeking funding to replenish the stocks of vaccines needed to rollout the outbreak campaign across the country to vaccinate all children between nine months and 14 years. Additional medicines to treat those already infected are also required.

Source: All Africa

Malaria control efforts saved 3.3 million since 2000, WHO says

Global efforts to curb malaria have saved the lives of 3.3 million people since 2000, cutting global death rates from the mosquito-borne disease by 45 percent and by half in children under 5, the World Health Organization said on Wednesday.

WHO said in its World Malaria Report 2013 that expanded prevention and control measures helped produce declines in malaria deaths and illness. Of the 3.3 million lives saved, most were in the 10 countries with the highest malaria burden and among children under age 5, the group most afflicted by the disease.

“Investments in malaria control, mostly since 2007, have paid off tremendously,” said Ray Chambers, the United Nations secretary-general’s special envoy for malaria.

According to the WHO report, child deaths fell to fewer than 500,000 in 2012.

Overall, there were an estimated 207 million cases of malaria in 2012, which caused some 627,000 deaths, according to the report, which includes information from 102 countries with malaria transmission.

The estimated number of malaria cases per 1,000 at-risk individuals – a figure that takes population growth into account – shows a 29 percent drop globally between 2000 and 2012, and a 31 percent drop in Africa.

During the same period, death rates per 1,000 at-risk individuals fell by 45 percent globally and 51 percent in children under age 5.

“This remarkable progress is no cause for complacency: absolute numbers of malaria cases and deaths are not going down as fast as they could,” WHO Director-General Dr Margaret Chan said in a statement accompanying the release of the report.

“The fact that so many people are infected and dying from mosquito bites is one of the greatest tragedies of the 21st century.”

FUNDING CUTS

Malaria is endemic in more than 100 countries worldwide but can be prevented by the use of bed nets and indoor spraying to keep the mosquitoes that carry the disease at bay. The mosquito-borne parasitic disease kills hundreds of thousands of people a year, mainly babies in the poorest parts of sub-Saharan Africa.

An estimated 3.4 billion people continue to be at risk for malaria, mostly in Southeast Asia and in Africa where around 80 percent of cases occur.

Chambers said progress against malaria has been threatened by funding cuts in 2011-2012, which translated into a flattening in the curve of the decline. The WHO noted significant drops in delivery of insecticide-treated bed nets in its 2013 report.

But that could begin to ease. Last month, the Global Fund to Fight AIDS, Tuberculosis and Malaria, UNICEF, the UK’s Department for International Development and the U.S. President’s Malaria Initiative agreed to provide over 200 million nets in the next 12 to 18 months, which will replace 120 million existing bed nets and provide 80 million new ones.

WHO also continues to track emerging parasite resistance to artemisinin, the core component of malaria drugs known as artemisinin-based combination therapies, or ACTs, and mosquito resistance to insecticides.

Four countries in Southeast Asia reported artemisinin resistance in 2013, and 64 countries found evidence of insecticide resistance, suggesting recent gains against malaria are still “fragile,” Dr Robert Newman, director of the WHO Global Malaria Programme, said in a telephone interview.

“The greatest threat to the future isn’t biological, but financial. It’s not having enough money to stay a step ahead,” Newman said.

Source: reuters

Cadila launches Mycidac-C : World’s first drug for lung cancer

Cadila Pharmaceuticals has announced the launch of Mycidac-C, an affordable, unique and innovative drug for the treatment of lung cancer.

Mycidac-C is an innovative research product for the patients suffering from Non Small Cell Lung Cancer (NSCLC). The drug has been approved for launch in India by the Drug Controller General of India (DCGI). It targets Desmocolin-3, a novel target, said the company in a statement.

According to the statement, Mycidac-C is a first in the class active immunotherapy as well as drug targeting Desmocollin-3. It is a breakthrough in the management of squamous cell NSCLC. There has been no significant innovation in management of squamous NSCLC since the introduction of platinum containing doublet in 1983. Besides affordability and other advantages, Mycidac-C has no systemic side effects during the treatment. Mycidac-C is to be used with platinum containing doublet therapy.

As per the World Health Organisation (WHO) report, approximately 1.25 million people are diagnosed with lung cancer every year worldwide. Around 30 per cent of them suffer from squamous NSCLC. Lung cancer kills more people than the three next commonest cancers combined.

Mycidac-C can be administered easily by trained paramedics, thus further reducing the cost of hospitalisation associated with other cancer therapy, according to the statement.

Rajiv I Modi, chairman and managing director, Cadila Pharmaceuticals, said, “It has taken us over a decade, a huge investment and a dedicated research and development team to develop this unique drug. We expect it to be available in the Indian market by December 2013. Thereafter, we will introduce it in other regions like SAARC countries and European markets over the next five years.”

Source: India Medical Times