High blood pressure continues to be a bigger problem in Southeastern US

 

One third of U.S. adults have high blood pressure, but in the southeastern part of the country the rate is well over half, according to a new study that finds too little is being done to reverse the problem.

The Southeast has been called the Stroke Belt because of well-known high rates of cardiovascular disease, including high blood pressure. But that knowledge has not led to changes, nor to a full understanding of the reasons for the population’s high risk, the study team reports.

“The rates have not changed,” though the U.S. has had treatment guidelines for high blood pressure since 1977, said one of the authors, Dr. Uchechukwu K. A. Sampson, an assistant professor of medicine at Vanderbilt University Medical Center in Nashville, Tennessee.

“The number of people who do not know that they have high blood pressure is the same,” he added.

High blood pressure is an established cause of death from cardiovascular disease and accounts for up to 7.5 million deaths worldwide each year, the researchers point out.

To investigate the persistently high rates of high blood pressure in the South, Sampson’s group used a large database with recent information on men and women in southern states covering the years 2002 to 2009.

They focused on 69,000 white and black adults with similarly low income and education levels – to eliminate poverty as a factor – and analyzed what other causes might be contributing to blood pressure problems.

Overall, they found that 57 percent of the study participants had high blood pressure. Blacks were nearly twice as likely as whites to be suffering from the disease, which has no symptoms of its own, but can lead to stroke or kidney damage if untreated.

But the racial difference was seen mainly among women. Fifty one percent of black and white men had high blood pressure, but the rates were 64 percent among black women and 52 percent among white women.

Obesity seemed to be a main driver of the problem, especially among whites, with the most severely obese having more than four times the risk of high blood pressure compared to normal weight men and woman.

Other factors linked to the likelihood of severe high blood pressure included high cholesterol, diabetes, a history of depression and a family history of heart disease.

The numbers Sampson’s group found have not changed from previous studies and that consistency is alarming, he said.

“Are they still the same factors people have found before?” Sampson said. “If they are, that is bad news, then that means we have not done what we should have done in the past few years.”

Of the study participants who knew they had high blood pressure, 94 percent were taking at least one blood pressure medication, which is a good thing, Sampson said. But only 30 percent were taking a diuretic medication that promotes water loss from the body. Diuretics should be one of the first-line medication options, the authors write.

Black people were twice as likely as whites to have high blood pressure without knowing it, Sampson said.

That racial difference did not change even when researchers accounted for differences in income and education, the authors write in the journal Circulation: Cardiovascular Quality and Outcomes.

All of this lines up with what doctors and researchers already knew, Sampson said.

Without specific studies, it’s hard to say why population rates have not gone down, and why so many people still do not know they have high blood pressure, and why so few are on diuretics, he said.

Women may not actually be more predisposed to high blood pressure, Sampson said, but they may be less aware of the risk than men.

Awareness efforts have historically focused on men when it comes to heart and blood pressure problems, but women are equally likely to have problems, he said.

“African American women are known to have a very high prevalence of hypertension and that its onset is significantly earlier than what is seen in white women,” Dr. John M. Flack said.

Flack is chair of the department of medicine at Wayne State University at the Detroit Medical Center in Michigan.

Source: news.nom


Scientists find possible new way of fighting high blood pressure

Researchers at Britain’s Bristol University removed nerve links between the brain and the carotid body blood pressure fell and remained low.

Scientists experimenting with rats have found that de-activating certain nerves in the neck can effectively treat high blood pressure – a discovery that could be an advance in tackling one of the world’s biggest silent killers.

Researchers at Britain’s Bristol University found that in rats with high blood pressure, when they removed nerve links between the brain and the carotid body – a nodule about the size of a grain of rice on the side of each carotid artery – the animals’ blood pressure fell and remained low.

The researcher’s results, published in the journal Nature Communications on Tuesday, have already led the team on to conduct a small human trial of the technique, with results expected at the end of this year.

Hypertension, or high blood pressure, is referred to by the World Health Organization as one of the world’s biggest silent killers because most people who have it can’t feel or see it.

It affects around one in three people worldwide and can cause stroke, heart attacks and kidney failure.

After diagnosis, treatment of high blood pressure needs to lifelong and many patients are able to manage their condition with anti-hypertension drugs. But experts say that for around 1 in 50 of them, medication does not help.

Julian Paton, who led this latest study at Bristol’s school of physiology and pharmacology, said while scientists already knew of a link between the carotid organs and hypertension, until now them “had absolutely no idea that they contributed so massively to the generation of high blood pressure.”

Tim Chico, as consultant cardiologist at the University of Sheffield who was not directly involved in the research, described the technique as “exciting and innovative” but cautioned that more work was needed to assess its effectiveness and safety before it could be considered for use in patients.

Normally, Paton explained, the carotid body acts to regulate the amount of oxygen and carbon dioxide in the blood.

It is stimulated when oxygen levels fall in the blood – such as when someone is holding their breath. This then causes a dramatic increase in breathing and blood pressure until blood oxygen levels are restored.

Having established that this response comes about through a nerve connection between the carotid body and the brain, Paton’s team decided to block the nerve endings in the neck and found that it swiftly brought their blood pressure down.

Jeremy Pearson, associate medical director at the British Heart Foundation, which part-funded this latest research, said all eyes are now on the human trial aiming to find out whether the treatment might work in people with high blood pressure who don’t get better with current drugs.

Tony Heagerty, a professor of medicine at Manchester University who was not involved in the study, said it was an interesting development which could “potentially avoid the use of drugs which have to be taken on a daily basis for many years.”
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