health tips

Switzerland may ban drivers from wearing high heels

This may give flat packing a new meaning for travelers to Switzerland.

The Alpine nation may soon ban drivers from wearing high heels and other types of shoes behind the wheel, The Sunday Times reports.

Police have been lobbying for the restrictions after a number of high-profile accidents tied to inappropriate footwear, including ski boots.

Drivers caught violating the new law could face a suspension of their license and up to three months in prison.

The specific kinds of footwear that will be affected have not yet been determined, but donate think you ll be able to just kick off your heels if you see a police car in your rear view mirror.

Barefoot driving is expected to be banned there as well.

Source: Bubble news

 

8 famous foods discovered by mistake

Some of the greatest discoveries are made by accident and it’s no exception when it comes to food. From a frozen treat to flaked wheat, here are eight famous foods that are the result of pure serendipity.

1Popsicles

As a childhood staple, it’s fitting that this sweet treat came to be after a discovery by a child. In 1905, 11-year-old Frank Epperson left a stirring stick, placed in a cup of powdered soda and water, on his porch overnight. When Epperson happened upon the frozen mixture the next day, he decided to call it an “Epsicle.” Eventually, his kids would refer to the frozen pop as Pop’s ‘sicle, causing Epperson to change the name. In 1923, Epperson sold the rights to Popsicle® and today, the company sells 2 billion ice pops annually, with cherry being the most popular flavor amongst its consumers.

Raisins

It’s believed that humans first discovered raisins when they stumbled upon a crop of dried grapes. The time period during which this occurred is still

debated, but the first accidental commercial raisin crop is said to have materialized in California in 1873. Two years later, vineyardist William Thompson introduced his thin-skinned, sweet tasting “Thompson Seedless” grapes, which today, are the basis for most raisins.

Ice Cream Cones

Some would argue that ice cream without an ice cream cone is nothing short of incomplete, so it’s impressive that this edible ice cream dish rose to fame after an impromptu act. The ice cream cone gained popularity in 1904 at the St. Louis World’s Fair when Syrian concessionaire, Ernest Hamwi, decided to roll up some of his crisp, waffle-like pastries (also known as zalabia) to help out a neighboring ice cream vendor who ran out of dishes.

Aspartame

File this one under ‘the time when accidently ingesting a chemical led not only to a positive outcome, but a revolutionary one.’ In 1965, scientist Dr. James Schlatter was working on an anti-ulcer drug when he went to lick his finger to pick up a piece of paper. His finger tasted sweet, so he traced back his steps and realized that the sweet-tasting substance was aspartame. Today, this popular low-calorie sweetener (which is about 200 times sweeter than sucrose) can be found in many popular foods.

Chocolate Chip Cookies

Talk about an accident that turned out oh-so-right. In the 1930’s, while preparing a batch of butter drop cookies for her guests at the Toll House Inn in Massachusetts, Ruth Wakefield decided to stick pieces of a NESTLÉ® chocolate bar into the cookie dough, expecting it to dissolve once baked. Instead, the chocolate maintained its shape. NESTLÉ® quickly caught wind of the discovery and placed Wakefield’s recipe on their chocolate bar wrappers, where it still remains today. In 1997, to honor the popular recipe’s origin, Massachusetts designated the chocolate chip cookie as its official state cookie. If you ever need some validation that failure can lead to success, take at look back at the beginnings of corn flakes. In 1898, W.K. Kellogg (who later became the founder of Kellogg’s) and his brother, Dr. John Harvey Kellogg, accidently produced a batch of flaked wheat berry after attempting to make granola. The Kellogg brothers then decided to experiment by flaking corn and the rest is history.

Corn Flakes

If you ever need some validation that failure can lead to success, take at look back at the beginnings of corn flakes. In 1898, W.K. Kellogg (who later became the founder of Kellogg’s) and his brother, Dr. John Harvey Kellogg, accidently produced a batch of flaked wheat berry after attempting to make granola. The Kellogg brothers then decided to experiment by flaking corn and the rest is history.

Chocolate Chip Cookies

Talk about an accident that turned out oh-so-right. In the 1930’s, while preparing a batch of butter drop cookies for her guests at the Toll House Inn in Massachusetts, Ruth Wakefield decided to stick pieces of a NESTLÉ® chocolate bar into the cookie dough, expecting it to dissolve once baked. Instead, the chocolate maintained its shape. NESTLÉ quickly caught wind of the discovery and placed Wakefield’s recipe on their chocolate bar wrappers, where it still remains today. In 1997, to honor the popular recipe’s origin, Massachusetts designated the chocolate chip cookie as its official state cookie. If you ever need some validation that failure can lead to success, take at look back at the beginnings of corn flakes. In 1898, W.K. Kellogg (who later became the founder of Kellogg’s) and his brother, Dr. John Harvey Kellogg, accidently produced a batch of flaked wheat berry after attempting to make granola. The Kellogg brothers then decided to experiment by flaking corn and the rest is history.

Lea & Perrins Worcestershire Sauce

The next time you slather this deliciously sweet, tangy sauce on your meal, know that without the mistake of two chemists, that meal might not be as tasty. In the early 1800’s, a man by the name of Lord Sandys appointed chemists John Lea and William Perrins to the task of recreating a recipe he had tasted in Bengal. Lea and Perrins attempted the sauce, but did not like the result, so they left the sauce in jars in a cellar. Two years later, the two stumbled across the sauce, decided to taste it and found something amazing: it actually tasted good. Today, Lea & Perrins Worcestershire Sauce is aged in a wooden cask for 18 months and is a popular dressing on meats and salads.

Yogurt

It’s believed that yogurt developed at a time when milk-producing animals became domesticated, possibly around 5,000 B.C. To transport the animal milk, the milk was often placed in sacks made from the stomachs of animals. It’s believed that the bacteria as well as the acidity from the lining of the stomachs prompted the milk to coagulate, forming the beginnings of yogurt.

Source: Fox news

 

People with Depression May Age Faster

People suffering from depression may be aging faster than other people, according to a new study from the Netherlands.

In the study of about 1,900 people who had major depressive disorders at some point during their lives, along with 500 people who had not had depression, researchers measured the length of cell structures called telomeres, which are “caps” at the end of chromosomes that protect the DNA during cell division. Normally, telomeres shorten slightly each time cells divide, and their length is thought to be an index of a cell’s aging.

The researchers found telomeres were shorter in people who had experienced depression compared with people in the control group. This suggests cellular aging in people with depression is accelerated by several years, the researchers said.

Source: Live Science

 

Sarepta shares plunge 60 percent after FDA questions drug trial

A view shows the U.S. Food and Drug Administration (FDA) logo at its headquarters in Silver SpringSarepta Therapeutics Inc lost more than 60 percent of its market value after it was advised by the U.S. health regulator to find new ways to test its flagship treatment for a rare muscle disorder.

The U.S. Food and Drug Administration (FDA), citing new data and the failed trial of a competing drug, said the design and goals of Sarepta’s current trial might not be sufficient to win marketing approval for its drug.

Sarepta’s shares fell 62 percent, wiping more than $750 million off the company’s market value and making the stock the biggest percentage loser on the Nasdaq on Tuesday afternoon. At least three brokerages downgraded the stock.

“Everything I thought could have gone wrong has gone wrong – and then more stuff has gone wrong,” said Chad Messer, an analyst at investment banking and asset management firm Needham & Co, who downgraded Sarepta’s stock to “hold” from “buy”.

Sarepta is developing the drug, eteplirsen, as a treatment for Duchenne muscular dystrophy (DMD), a degenerative disorder that hampers muscle movement and affects one in 3,600 newborn boys.

Investors had been betting on a breakthrough.

Before Tuesday’s fall, Sarepta’s stock had more than doubled since October 2012, when data from a mid-stage trial showed that eteplirsen significantly improved walking ability in DMD patients.

But the FDA has now suggested that eteplirsen be tested against a placebo in a new, and potentially larger, trial, Sarepta said on Tuesday.

A placebo-controlled trial, it said, would be better than current trials in removing bias in walking ability that might be susceptible to individual effort or patient care.

“…It seems worthwhile to consider selection of other endpoints and/or populations for the next trial of eteplirsen,” Sarepta said it was told by the FDA in a meeting last week.

In its remarks, the FDA cited the recent failure of the trial of a rival drug, drisapersen, being developed by GlaxoSmithKline and Prosensa Holding NV.

That drug, like eteplirsen, works by increasing the production of a protein called dystrophin, the lack of which is the chief cause of DMD.

It failed to show a statistically significant improvement in the distance that DMD patients could walk in six minutes compared with placebo in a late-stage trial in September.

Prosensa’s shares, which had lost about 85 percent of their value since the announcement of drisapersen’s trial failure, were up 19 percent on Tuesday.

DOWNGRADES

Sarepta, previously known as AVI Biopharma, has gone more than three decades without bringing a drug to market. Analysts had previously said that they expected the company to ask for eteplirsen’s approval to be accelerated.

Sarepta said the FDA request would delay the initiation of dosing in a confirmatory study until at least the second quarter of 2014. A follow-up meeting with the regulator to discuss the confirmatory study design is scheduled this month.

“The likelihood of an accelerated approval at this point is very low. It seems like a long shot to me that the FDA is going to reverse position,” said Edward Tenthoff, analyst at Piper Jaffray.

Tenthoff, who cut his price target on the stock to $20 from $58, said he expected the FDA to require a confirmatory study with a two-year follow-up, which could delay the potential approval of eteplirsen to late 2017 or early 2018.

Both Tenthoff and Needham & Co’s Messer said the FDA and Sarepta would probably need to agree a new endpoint for trials, given the regulator’s concerns about the six-minute-walk trial.

“They thought they will be able to file early on limited data,” said Messer. “The FDA is not only saying forget about that, they probably also cannot do a full filing, and now it’s even questionable as to what the next study has to look like.”

Janney Capital Markets also downgraded Sarepta’s stock to “sell” from “neutral,” while Leerink Swann cut its price target to $17 from $44.

Sarepta’s shares were down 62 percent at $14.06 in early afternoon trading.

Source: Reuters

 

Mothers in UK offered Euro 200 for breastfeeding

breastfeedingNew mothers are to be offered up to £200 in shopping vouchers to encourage them to breastfeed their babies.

The pilot scheme is being targeted at deprived areas of South Yorkshire and Derbyshire and funded through collaboration between government and the medical research sector.

A third area is expected soon with the plan to trial it on 130 women who have babies from now until March.

If successful, a nationwide pilot could be rolled out in England next year.

The use of financial incentives is not new in the NHS.

It has been tried before to encourage people to quit smoking as well as lose weight.

Culture

But this is the first time it has been tried on such a scale for breastfeeding.

breastfeeding1

Under the scheme mothers from specific parts of Sheffield and Chesterfield will be offered the vouchers, which they can then use in supermarkets and high street shops.

The areas have been chosen because they have such low breastfeeding rates. On average just one in four mothers are breastfeeding by the six- to eight-week mark compared with a national average of 55%.

To qualify for the full £200 of rewards, the women will have to breastfeed until six months.

However, it will be frontloaded – enabling those taking part to get £120 for breastfeeding for the first six weeks.

Midwives and health visitors will be asked to verify whether the women are breastfeeding.

The team behind the project said breastfeeding was a cause of health inequalities, pointing to research that showed it helped prevent health problems such as upset stomachs and chest infections as well as leading to better educational attainment.Breastfeeding expert Geraldine Miskin Mums need to have practical advice

Dr Clare Relton, the Sheffield University expert leading the project, said she hoped the financial incentives would create a culture where breastfeeding was seen as the norm.

“It is a way of acknowledging both the value of breastfeeding to babies, mothers and society,” she added.

But Janet Fyle, of the Royal College of Midwives, questioned the initiative: “The motive for breastfeeding cannot be rooted by offering financial reward. It has to be something that a mother wants to do in the interest of the health and well-being of her child.”

She said the answer lay in making sure there was enough staff available to provide comprehensive support to new mothers after birth.

Source: BBC

Cancer Survivor to Return to Golf After 20 Months

When Jarrod Lyle returns to golf after a 20-month layoff at the Australian Masters, he expects some teary eyes on the tee.

Lyle is 32 years old and will be playing his first tournament since his second fight with myeloid leukemia — his first came at 17. This time, he’ll have his wife and young daughter with him Thursday when he starts a tournament that he’s not sure he’s physically ready to finish should he make the 36-hole cut.

“Just walking to that first tee and teeing the ball up and trying to hit it — that’s probably going to be the hardest thing,” Lyle said Tuesday at Royal Melbourne.

“It’s just going to let a whole lot of stuff out. Hopefully when that ball flies I can just get on to playing golf and put everything behind me and just get back to the golfer that I am.”

Lyle, then a regular on the U.S. PGA Tour, was diagnosed with his second bout of leukemia in March 2012 just before the birth of his daughter, Lusi. Lyle’s wife, Briony, became pregnant despite medical advice that Lyle’s first bout of cancer and the resulting chemotherapy would leave him sterile.

With a medical exemption to return to the PGA Tour whenever he feels he’s ready — and it might not be until late in 2014 — Lyle has found his second bout of cancer illuminating.

On the positive side, he knew what to expect, and anti-nausea drugs to counteract the chemotherapy had improved in the 15 years between his illnesses.

On the downside, because he had the disease once, it was harder to overcome twice. The first time, he spent two to three weeks at a stretch in the hospital. The second time, it often was four or five weeks or more. He’s lost weight, and his strength.

And he’s still not out of the usual five-year cancer-free time frame, as he thought he had done as a teenager.

Briony and Lusi, nearly 2, will be among a big group of friends and family supporting him at Royal Melbourne on Thursday on Friday. And against all odds, maybe the weekend.

Lyle will tee off just after midday on the first hole Thursday with two veterans to help him along — fellow Australian and 2006 U.S. Open champion Geoff Ogilvy, and Brendon de Jonge, the Zimbabwean who represented the International team at the recent Presidents Cup.

Many of Lyle’s fans will be wearing specially designed yellow shirts and hats to support his involvement in the children’s cancer charity Challenge.

When Tiger Woods won the Arnold Palmer Invitational at Bay Hill in 2012, he was wearing a “Leuk the Duck” pin on his cap. The cartoon duck is a mascot for kids who come through the Challenge charity, and Woods wore it out of respect for Lyle, as did many players in the field not long after Lyle’s second cancer fight was known.

“To have the support of all those guys, guys that I am not really close with as well, it is nice,” Lyle said at the time. “It is nice to know they still care and want to know how you are going.”

On Thursday, Lyle won’t forget that support and knows where his heart will be.

“I’m going to dedicate this first tee shot to everybody that’s done that over the years or over the last 20 months,” he said. “Everyone who has got in contact with us and given us support.”

Source: abc news

 

 

Health ‘score’ on food packages may help healthier choices

For people trying to wade though nutrition labels and choose healthy options, a front-of-package food label that boils down nutrition information to a single “score” may be the most user-friendly approach, a new study suggests.

In recent years, the fronts of some food packages have been decorated with short food labels, which are intended to briefly summarize a product’s nutrition, and make unhealthy ingredients (such as high levels of saturated fat) highly visible to consumers.

However, there is currently no standard for what information needs to be on these labels, leading to a variety of front-of-package food labeling systems that may confuse consumers, said study researcher Christina A. Roberto, a psychologist and epidemiologist at the Harvard School of Public Health.

Experts say that a single, uniform food label should be adopted, but before this can happen, researchers need to know what works best. The new study attempted to help answer this question by comparing five front-of-package food labeling systems, as well as packages with no label.

More than 1,000 people, about half of whom were actively trying to lose weight, were randomly assigned to view food products with one of the following labels:

A “Facts Up Front” label, which was created by the food industry and contains information about calories, saturated fat, sodium and sugars, as well as any noteworthy vitamins.

A “NuVal” label, a proprietary labeling system that gives products a score from 1 to 100 based on a product’s nutritional quality; higher scores denote healthier products.

A single traffic light symbol, which is colored red, yellow or green based on the healthfulness of the product.

A label depicting multiple “traffic lights,” in which different nutrients get their own red/yellow/green symbol (such as green for saturated fat, but yellow for sodium).

A star system, in which a product is given 0 to 3 stars based on its nutrition quality.

No label

In a simulated online shopping task, participants viewed different soups, cereals, beverages, rice products and ice creams, and were asked to choose which products they would like to eat this week.

The only food labeling system that prompted people to pick healthier soups was the NuVal label, the study found.

When shown two products and asked, “Which is healthier?” the NuVal label, along with the multiple traffic-light label, worked best to help participants identify which product was truly healthier.

However, those who viewed the NuVal label were able to choose the healthier product in half the time as those who viewed the multiple traffic-light label, Roberto said.

Based on these preliminary data, NuVal is probably “the most user-friendly,” Roberto said. The simplicity of the system (with just one number), and the fact that it allows users to compare products with high and low numbers, may be helpful to consumers, Roberto said.

However, much more research is needed to confirm the findings, including studies of “real-world” purchasing scenarios, Roberto said.

In addition, it’s not clear how much front-of-package labels help consumers overall. In the study, the food labels did not help consumers pick healthier cereals, beverages, rice products or ice creams.

However, Roberto argues these labels have a purpose.

“It might not massively shift behavior, but I think it’s still worth informing consumers,” Roberto said. “It might influence behavior some of the time, and that can still have an important and meaningful public health impact.”

And if front-of-package labels were mandatory — as proposed in a recent congressional bill — food companies may be pressured change their products so they are healthier (to get a higher NuVal score, or more “green” traffic lights, for instance).

If a uniform front-of-package label system is rolled out, consumers should be educated regarding how to interpret and use the labels, Roberto said.

The study was presented last week at the American Public Health Association meeting in Boston.

Source: Yahoo News

 

Brain stem abnormalities linked to SIDS, study shows

brain abnormaltiesUnderlying brain stem abnormalities may be responsible for the onset of sudden infant death syndrome (SIDS), a condition that causes babies to die unexpectedly in their sleep, Counsel and Heal reported.

In a study published in the journal Pediatrics, researchers reviewed the cases of 50 infants who died of SIDS. Though some of the infants studied were sleeping in unsafe environments – such as in a face-down position– the researchers discovered that regardless of sleep conditions, all of the babies studied showed abnormalities in their brain stem chemicals.

The researchers believe that these abnormalities prevented the infants from waking up when they experienced trouble breathing. However, the researchers said parents should still make every effort to ensure that their infants sleep in a safe environment.

“We have to find ways to test for this underlying vulnerability in living babies and then to treat it. Our team is focused now upon developing such a test and treatment,” said study author Dr. Hannah Kinney, a neuropathologist at Boston Children’s Hospital. “Safe sleep practices absolutely remain important, so these infants are not put in a potentially asphyxiating situation that they cannot respond to.”

Source: News.nom

Myth or fact? Coconut oil helps treat Alzheimer’s disease

With more than 5 million Americans suffering from Alzheimer’s disease, many people are looking to alternative treatments for help.

We received this email from a concerned viewer:
Dear Dr. Manny,
Does coconut oil help prevent Alzheimer’s disease?
Thanks,
Darrell

Processing coconut oil produces a kind of fat called caprylic acid, which the body then breaks down into substances called ketone bodies.

The theory behind using coconut oil for the prevention or treatment of Alzheimer’s disease is that these ketone bodies can provide an alternative source of energy to brain cells that have lost their ability to use glucose as a result of the disease.

“There was one study that seems to have sparked sort of a firestorm of hope,” said Chris Kilham, the Medicine Hunter. “That was a test-tube study, showing a change in the behavior of beta-amyloid plaque cells – which are the same kinds of cells that accumulate in the brainstem during Alzheimer’s – when they were exposed to ketones derived from coconut oil.”

Kilham said that researchers at the University of South Florida Health Byrd Alzheimer’s Institute are currently studying the effects of coconut oil on a small group of Alzheimer’s patients in a first-of-its-kind clinical trial. But he added that at this point in time, there is no science to back up the claims that coconut oil is beneficial for Alzheimer’s disease.

“It may be in fact beneficial, but we don’t know that yet,” said Kilham. “There are some anecdotal studies, people who say that partners of theirs have started taking …virgin coconut oil daily, and they’ve improved. This may be so, but right now, today, I don’t want to give out false hope. There’s no good science on this, and until there is, I’m holding off making a recommendation.”

Currently, there is no cure for Alzheimer’s disease, but there are treatments that may help with both cognitive and behavioral symptoms to improve a patient’s quality of life.

Source: Fox news

 

FDA Takes Two Important Actions on Drug Shortages

The U.S. Food and Drug Administration is taking two actions to further enhance the agency’s ongoing efforts to prevent and resolve drug shortages, a significant public health threat that can delay, and in some cases even deny, critical care for patients. Following the President’s 2011 Executive Order on reducing drug shortages, the number of new shortages in 2012 was 117, down from 251 in 2011.

Today’s announcements build on this work. First, the FDA is releasing a strategic plan called for in the Food and Drug Administration Safety and Innovation Act (FDASIA) of 2012 to improve the agency’s response to imminent or existing shortages, and for longer term approaches for addressing the underlying causes of drug shortages. The plan also highlights opportunities for drug manufacturers and others to prevent drug shortages by promoting and sustaining quality manufacturing.

Second, the FDA issued a proposed rule requiring all manufacturers of certain medically important prescription drugs to notify the FDA of a permanent discontinuance or a temporary interruption of manufacturing likely to disrupt their supply. The rule also extends this requirement to manufacturers of medically important biologic products. The proposed rule implements the expanded early notification requirements included in FDASIA.

“The complex issue of drug shortages continues to be a high priority for the FDA, and early notification is a critical tool that helps mitigate or prevent looming shortages,” said Janet Woodcock, M.D., director of the FDA’s Center for Drug Evaluation and Research (CDER). “The FDA continues to take all steps it can within its authority, but the FDA alone cannot solve shortages. Success depends upon a commitment from all stakeholders.”

Early notification gives the FDA time to:

  • work with manufacturers to investigate the issue leading to the manufacturing disruption;
  • identify other manufacturers who can make up all or part of the shortfall; and
  • expedite inspections and reviews of submissions from manufacturers of drugs that may prevent or mitigate a shortage.

Early notification from manufacturers about possible shortages, as requested in the President’s Executive Order 13588 of Oct. 31, 2011 and then codified into law in FDASIA, has enabled the FDA to work with manufacturers to restore production of many lifesaving therapies. Since the Executive Order, there has been a 6-fold increase in notifications to the FDA.

The notifications received under the existing requirements have resulted in real progress in addressing shortages. The FDA helped prevent 195 drug shortages in 2011 and 282 drug shortages in 2012, leading to a reduced number of new shortages in 2012. The expanded early notification requirements would further enhance the FDA’s ability to address issues prior to the occurrence of a shortage.

The strategic plan, which was required by FDASIA and is being sent to Congress today, describes actions the FDA will undertake to improve its current efforts to respond to early notifications of a potential shortage. These include:

  • improving the FDA’s communications about shortages, such as launching a new mobile app, so that individuals can instantaneously access drug shortage information via their smart phones;
  • clarifying manufacturers’ roles and responsibilities by encouraging them to engage in certain practices that will reduce the likelihood of a shortage; and
  • updating the FDA’s internal procedures for responding to early notifications of potential shortages.

The strategic plan also describes efforts the FDA is considering to address the manufacturing and quality issues that are most often the root cause of drug shortages. These include:

  • broader use of manufacturing metrics to assist in the evaluation of manufacturing quality, as well as incentives for high-quality manufacturing;
  • internal organization improvements to focus on quality, including a proposed Office of Pharmaceutical Quality within CDER; and
  • Risk-based approaches to identify early warning signals for manufacturing and quality problems.

Source: drugs