Diabetes battle ‘being lost’ as cases hit record 382 million

The world is losing the battle against diabetes as the number of people estimated to be living with the disease soars to a new record of 382 million this year, medical experts said on Thursday.

The vast majority have type 2 diabetes – the kind linked to obesity and lack of exercise – and the epidemic is spreading as more people in the developing world adopt Western, urban lifestyles.

The latest estimate from the International Diabetes Federation is equivalent to a global prevalence rate of 8.4 percent of the adult population and compares to 371 million cases in 2012.

By 2035, the organization predicts the number of cases will have soared by 55 percent to 592 million.

“The battle to protect people from diabetes and its disabling, life-threatening complications is being lost,” the federation said in the sixth edition of its Diabetes Atlas, noting that deaths from the disease were now running at 5.1 million a year or one every six seconds.

People with diabetes have inadequate blood sugar control, which can lead to a range of dangerous complications, including damage to the eyes, kidneys and heart. If left untreated, it can result in premature death.

“Year after year, the figures seem to be getting worse,” said David Whiting, an epidemiologist and public health specialist at the federation. “All around the world we are seeing increasing numbers of people developing diabetes.”

He said that a strategy involving all parts of society was needed to improve diets and promote healthier lifestyles.

The federation calculates diabetes already accounts for annual healthcare spending of $548 billion and this is likely to rise to $627 billion by 2035.

Worryingly, an estimated 175 million of diabetes cases are as yet undiagnosed, so a huge number of people are progressing towards complications unawares. Most of them live in low- and middle-income countries with far less access to medical care than in the United States and Europe.

The country with the most diabetics overall is China, where the case load is expected to rise to 142.7 million in 2035 from 98.4 million at present.

But the highest prevalence rates are to be found in the Western Pacific, where more than a third of adults in Tokelau, Micronesia and the Marshall Islands are already living with the disease.

Pharmaceutical companies have developed a range of medicines over the years to counter diabetes but many patients still struggle to control their condition adequately, leading to a continuing hunt for improved treatments.

Novo Nordisk, Sanofi and Eli Lilly are all major suppliers of insulin and other diabetes therapies.

Source: Reuters

 


Weight-loss surgery yields lasting improvement in health

Fifteen years after they have weight-loss surgery, almost a third of patients who had Type 2 diabetes at the time they were operated on remain free of the metabolic disorder, a new study says. And six years following such surgery, patients had shaved their probability of suffering a heart attack over the next 10 years by 40%, their stroke risk by 42%, and their likelihood of dying over the next five years by 18%, additional research has concluded.

The two studies, both presented Wednesday in Atlanta at the Obesity Society’s annual meeting, offer the first indications of weight-loss surgery’s longer-term health benefits for patients. While researchers have demonstrated dramatic improvements in many bariatric patients’ metabolic function in the short term, the durability of those improvements has been unclear.

Research suggests that over several years, many bariatric patients regain some of the weight they lose in the first two years — a fact that has raised doubts about the cost-effectiveness of the surgery, which can cost $20,000 to $25,000 for the initial procedure, plus a wide range of costs to treat complications after surgery.

The new studies’ findings those patients’ health prospects remain better for several more years may make weight-loss surgery a more appealing treatment for insurers to cover, and for obese patients with health concerns to seek out.

The study that followed 604 bariatric patients in Sweden for 15 years found that in the first two years after surgery, 72% achieved diabetes remission: They were able to cease taking medication for the metabolic condition. After 15 years, a little more than half of those had diabetes again. But 31% had remained in remission.

By contrast, only 16% of the comparison group — similarly obese patients with diabetes who did not get surgery — had seen their diabetes remit in the first two years. At 15 years out, diabetes remission was six times likelier in those who had surgery than in the those who did not.

In another study, researchers at the Cleveland Clinic in Ohio followed bariatric patients for an average of six years after surgery. They tallied those patients’ likelihoods of developing a wide range of health outcomes at the time of surgery and six years later, and compared them. To do so, they used the Framingham risk calculator to estimate the before-and-after 10-year risks of heart disease, stroke, death, kidney disease and complications such as diabetic retinopathy and poor circulation.

(The Framingham risk calculator is derived from probabilities gleaned from following more than 10,000 subjects in Framingham, Mass., in the Framingham Heart Study, which started in 1948.)

In this study, the bariatric patients lost 60% of their excess weight and 61% saw their diabetes remit after surgery. Overall their risk of having coronary heart disease, stroke or peripheral heart disease dropped by 27%.

Bariatric surgeon Dr. John Morton, a professor of medicine at Stanford University who was not involved in either study, suggested that the results of more modern bariatric surgical procedures may be superior. He added that reducing the stress of obesity on the body, even if some weight returns, may improve a patient’s long-term health prospects.

“Carrying extra weight can carry forth year to year,” said Morton, who is president-elect of the American Society for Metabolic and Bariatric Surgery, which cosponsored the Obesity Society’s Atlanta conference. He likened long-term obesity to smoking cigarettes for years, suggesting that the number of years a person remains obese (or smokes) may interact with their degree of obesity (or how much they smoke) to influence his or her likelihood of developing health problems.

“Any removal of that extra weight and inflammation is a help,” Morton said.

Source: Los Angeles Times

 


Indian Specialist Hospital Reduces Prices for Patients

Efforts by the federal government to curtail capital flights from the country in form of medical tourism received a boost Wednesday, as the only Indian specialist hospital in Nigeria, Primus International Super Specialty Hospital announced a downward review of all its medical charges to 30 percent, including offer of free consultancy in the month of November.

According to the management of the hospital, the decision to crash the hospital fees is part of its Corporate Social Responsibility (CSR) to open its services and state of the art equipments to Nigerian patients, majority of whom could not afford to go abroad.

The move is seen as a strategic measure to halt foreign medical tourism by Nigerian patients who travel abroad for treatment, which is believed to cost the nation a whopping $300 million to $400 million in foreign exchange per annum.

The hospital’s Public Relations Officer, (PRO) Alhaji Umaru Jibia, in a statement made available to journalists in Abuja, said the hospital, in addition to providing free consultation to patients in the area of joint replacement, spine problem, internal medicine, diabetes, ENT, gynecology, neuro surgery, dental, ophthalmology and general surgery, was also reducing the cost of medical treatment to help low income earners in the country.

He added: “MRI charges will be from N50, 000 onwards, while CT scan will be from N25, 000 onwards. Radiology, laboratory services will cost 30 per cent less, while Pharmacy drugs will cost 20 per cent less. The surgical procedures are at very reasonable charges during the camp period.”

The reduction of hospital prices came at a time the government was working for a workable framework that would put a stop to the increasing cases of capital flights due to frequent medical overseas trips by Nigerians.

Since its establishment in Abuja, the hospital had been conducting free camps in the city and its environs, where 23,000 patients have benefited from free consultation and medical other services.

Source: This day Live


Philanthropist’s gift a big bang for stem cell research

A philanthropist who made his money as a credit card provider is giving $100 million to human stem-cell research.

The money will go to the University of California at San Diego during the next five years as researchers reach certain milestones, said T. Denny Sanford, who founded First Premier Bank here and offers low-limit Master cards and Visas to customers with poor credit through Premier Bankcard. United National Corp., where Sanford is now chief executive, owns both companies.

“This, in my opinion, is the medicine of the future,” he said. “The potential of stem cells is just unbelievable.”

The money will support the hiring of 20 or more scientists and efforts to recruit patients for drug trials along with new construction at the San Diego complex.

The donation pushes Sanford past the $1 billion mark for total gifts to health care and research, he said.

Sanford, 77, has homes in South Dakota, Arizona and California. On Oct. 19, he suffered a pulmonary embolism — a blood clot in the lungs — while on a hunting trip with friends near Gregory, S.D., about 140 miles west of here.

He said he was saved because of a middle-of-the-night medical flight to Sanford University of South Dakota Medical Center here, helicopter and plane flights made possible in part because of donations he has made to what is now Sanford Health system.

“I was within minutes or hours of death,” he said. His physician here, Dr. Eric Larson, said Sanford is doing fantastic, playing golf regularly and exercising on an elliptical machine, less than a month after getting clot-busting medications to treat the condition.

Most of Sanford’s donations, about $700 million, have gone to the Sanford Health. He has pledged to give all his money away. He said he still has close to $1 billion.

The $100 million he is committing to UC San Diego is the lead resource in a project that officials say will cost a total of $275 million.

What now is called the Sanford Consortium for Regenerative Medicine includes scientists from five institutions — UC San Diego, Sanford-Burnham, Scripps, the Salk Institute for Biological Studies and the LaJolla Institute for Allergy and Immunology.

“Overall, the effort is to bring stem cell research into human clinical trials,” said Debra Kain, director of health sciences research communications at UC San Diego.

In Sioux Falls, Sanford made a $400 million donation to the nonprofit medical center in 2007 and established four priorities, one of which was curing a major disease that officials later pegged as Type 1 diabetes. Another of his donations here, $100 million in 2011, is for research and treatment for breast cancer. His mother, Edith, died of the disease when he was 4 years old.

This gift is different because he has no personal or family connection to the neurological diseases he hopes that stem cell research can address.

Research so far has been instructive on the use of mice and monkeys, so it’s time now to extend the effort to humans, he said.

“We are excited about some major potential cures, particularly with neurological diseases like Lou Gehrig’s disease, or spinal cord injuries,” Sanford said. Lou Gehrig’s disease, also called amyotrophic lateral sclerosis, affects nerve cells in the brain and spinal cord that control muscle movement. It has no cure.

Sanford is excited that the work could lead several directions.

“It could be spinal cord injuries, Alzheimer’s, Parkinson’s, eventually heart and cancer and diabetes,” he said.

Source: USA Today

 


IBM opens global research lab in Africa IBM’s

12th global research lab was opened here last week. It is designed to conduct applied and far-reaching exploratory research into the big challenges of the African continent and deliver commercially viable innovations that impact people’s lives.

 The facility features one of Africa’s most powerful computer hubs, giving IBM researchers the ability to analyse and draw insight from vast amounts of data in search for solutions to Africa’s challenges such as energy, water, transportation, agriculture, healthcare, financial inclusion, human mobility and public safety.

“The establishment of this research laboratory underpins the government’s commitment to innovation ecosystems that are already available in Kenya,” said the president of Kenya, Uhuru Kenyatta. The lab is supported by the Kenyan ICT Authority.

The lab’s research agenda will include the development of cognitive computing technologies that integrate learning and reasoning capabilities, enabling experts to make better decisions in areas such as healthcare delivery and financial services.

“We are currently experiencing the emergence of a new Africa – one where science and technology are enabling a pivotal ‘leap frog’ moment allowing governments and businesses to drive economic growth, raise the standard of living and compete with their global counterparts,” said Kamal Bhattacharya, director, IBM Research-Africa.

“The launch of Africa’s first full-scale, technology research facility will help lay the foundation for the continent’s future scientific and economic independence,” he added. Nicholas Nesbitt, country general manager, East Africa, said it was not just about science and technology, “but also about innovating new business models and partnering with local enterprises to ensure that our new solutions have the maximum impact on business and society.”

Source: The Times of India

 


Biosensor to detect brain injuries during heart surgery

 

Scientists have developed a fingernail-sized biosensor that could alert doctors when serious brain injury occurs during heart surgery.

Johns Hopkins engineers and cardiology experts teamed up to develop the device and demonstrated in lab tests that the prototype sensor had successfully detected a protein associated with brain injuries.

“Ideally, the testing would happen while the surgery is going on, by placing just a drop of the patient’s blood on the sensor, which could activate a sound, light or numeric display if the protein is present,” said the study’s senior author, Howard E Katz, a Whiting School of Engineering expert in organic thin film transistors, which form the basis of the biosensor.

The project originated about two years ago when Katz, who chairs the Department of Materials Science and Engineering, was contacted by Allen D Everett, a Johns Hopkins Children’s Center pediatric cardiologist who studies biomarkers linked to pulmonary hypertension and brain injury.

Everett sought an engineer to design a biosensor that responds to glial fibrillary acidic protein (GFAP), which is a biomarker linked to brain injuries.

“If we can be alerted when the injury is occurring then we should be able to develop better therapies. We could improve our control of blood pressure or redesign our cardiopulmonary bypass machines,” Everett said.

“We could learn how to optimise cooling and rewarming procedures and have a benchmark for developing and testing new protective medications,” Everett added.

At present, Everett said, doctors have to wait years for some brain injury-related symptoms to appear. That slows down the process of finding out whether new procedures or treatments to reduce brain injuries are effective.

“The sensor platform is very rapid. It’s practically instantaneous,” Everett said.

To create this sensor, Katz turned to an organic thin film transistor design.

The sensing area is a small square, 3/8ths-of-an-inch on each side. On the surface of the sensor is a layer of antibodies that attract GFAP, the target protein.

When this occurs, it changes the physics of other material layers within the sensor, altering the amount of electrical current that is passing through the device.

These electrical changes can be monitored, enabling the user to know when GFAP is present.

“This sensor proved to be extremely sensitive. It recognised GFAP even when there were many other protein molecules nearby. As far as we’ve been able to determine, this is the most sensitive protein detector based on organic thin film transistors,” Katz said.

The study was published in the journal Chemical Science.

Source:  Zee News


Complex stent procedure performed on one-month-old baby

Complex stent procedure performed at Fortis Escort Heart Institute, New Delhi on a month old, 1.8 kg baby. (L-R) Dr S Radhakrishnan, director, paediatric and congenital heart diseases, FEHI and Dr Neeraj Awasthy, paediatric cardiologist, FEHI with the patient’s family.

Fortis Escorts Heart Institute (FEHI) has conducted a life-saving complex stent procedure on a one-month-old premature baby weighing 1.8 kg by a team of doctors comprising of Dr S Radhakrishnan, director, pediatric and congenital heart diseases and Dr Neeraj Awasthy, pediatric cardiologist. According to Fortis Escorts, this is the first case in India, with the lowest recorded weight and age of a baby undergoing a complex stent procedure. Her treatment has been funded by FEHI.

The baby was referred to FEHI by a government hospital in Delhi when she stopped breathing and showed signs of heart problems. The baby was immediately put on ventilator and was oxygen dependent for three weeks.

The artery going towards her lungs were found obstructive and this made her treatment complicated and high risk.

Explaining the complexity involved in the operation, Dr Radhakrishnan said, “Initially we kept the baby under ventilation for few days and when she started responding to our treatment, we decided to wean her off the ventilation. On further examination, it was found that the right ventricular outflow track was blocked and stent procedure should be performed. The baby would need a future surgery once she weighs 8-9 kg.”

Dr Awasthy said, “Given the multiple complexities of the case, her prognosis has been very good. When the case first came to us, her survival was a question. Such a case had never been attempted before anywhere in India. Today, after the surgeries, she is responding well to her treatment protocol.”

He added, “As the hospital is technologically equipped with advanced smaller size equipment to manage such complex cases, we were confident to go ahead and perform such a complex procedure which demanded additional vigilance and support.”

Source: India Medical Times


Switzerland may ban drivers from wearing high heels

This may give flat packing a new meaning for travelers to Switzerland.

The Alpine nation may soon ban drivers from wearing high heels and other types of shoes behind the wheel, The Sunday Times reports.

Police have been lobbying for the restrictions after a number of high-profile accidents tied to inappropriate footwear, including ski boots.

Drivers caught violating the new law could face a suspension of their license and up to three months in prison.

The specific kinds of footwear that will be affected have not yet been determined, but donate think you ll be able to just kick off your heels if you see a police car in your rear view mirror.

Barefoot driving is expected to be banned there as well.

Source: Bubble news

 


8 famous foods discovered by mistake

Some of the greatest discoveries are made by accident and it’s no exception when it comes to food. From a frozen treat to flaked wheat, here are eight famous foods that are the result of pure serendipity.

1Popsicles

As a childhood staple, it’s fitting that this sweet treat came to be after a discovery by a child. In 1905, 11-year-old Frank Epperson left a stirring stick, placed in a cup of powdered soda and water, on his porch overnight. When Epperson happened upon the frozen mixture the next day, he decided to call it an “Epsicle.” Eventually, his kids would refer to the frozen pop as Pop’s ‘sicle, causing Epperson to change the name. In 1923, Epperson sold the rights to Popsicle® and today, the company sells 2 billion ice pops annually, with cherry being the most popular flavor amongst its consumers.

Raisins

It’s believed that humans first discovered raisins when they stumbled upon a crop of dried grapes. The time period during which this occurred is still

debated, but the first accidental commercial raisin crop is said to have materialized in California in 1873. Two years later, vineyardist William Thompson introduced his thin-skinned, sweet tasting “Thompson Seedless” grapes, which today, are the basis for most raisins.

Ice Cream Cones

Some would argue that ice cream without an ice cream cone is nothing short of incomplete, so it’s impressive that this edible ice cream dish rose to fame after an impromptu act. The ice cream cone gained popularity in 1904 at the St. Louis World’s Fair when Syrian concessionaire, Ernest Hamwi, decided to roll up some of his crisp, waffle-like pastries (also known as zalabia) to help out a neighboring ice cream vendor who ran out of dishes.

Aspartame

File this one under ‘the time when accidently ingesting a chemical led not only to a positive outcome, but a revolutionary one.’ In 1965, scientist Dr. James Schlatter was working on an anti-ulcer drug when he went to lick his finger to pick up a piece of paper. His finger tasted sweet, so he traced back his steps and realized that the sweet-tasting substance was aspartame. Today, this popular low-calorie sweetener (which is about 200 times sweeter than sucrose) can be found in many popular foods.

Chocolate Chip Cookies

Talk about an accident that turned out oh-so-right. In the 1930’s, while preparing a batch of butter drop cookies for her guests at the Toll House Inn in Massachusetts, Ruth Wakefield decided to stick pieces of a NESTLÉ® chocolate bar into the cookie dough, expecting it to dissolve once baked. Instead, the chocolate maintained its shape. NESTLÉ® quickly caught wind of the discovery and placed Wakefield’s recipe on their chocolate bar wrappers, where it still remains today. In 1997, to honor the popular recipe’s origin, Massachusetts designated the chocolate chip cookie as its official state cookie. If you ever need some validation that failure can lead to success, take at look back at the beginnings of corn flakes. In 1898, W.K. Kellogg (who later became the founder of Kellogg’s) and his brother, Dr. John Harvey Kellogg, accidently produced a batch of flaked wheat berry after attempting to make granola. The Kellogg brothers then decided to experiment by flaking corn and the rest is history.

Corn Flakes

If you ever need some validation that failure can lead to success, take at look back at the beginnings of corn flakes. In 1898, W.K. Kellogg (who later became the founder of Kellogg’s) and his brother, Dr. John Harvey Kellogg, accidently produced a batch of flaked wheat berry after attempting to make granola. The Kellogg brothers then decided to experiment by flaking corn and the rest is history.

Chocolate Chip Cookies

Talk about an accident that turned out oh-so-right. In the 1930’s, while preparing a batch of butter drop cookies for her guests at the Toll House Inn in Massachusetts, Ruth Wakefield decided to stick pieces of a NESTLÉ® chocolate bar into the cookie dough, expecting it to dissolve once baked. Instead, the chocolate maintained its shape. NESTLÉ quickly caught wind of the discovery and placed Wakefield’s recipe on their chocolate bar wrappers, where it still remains today. In 1997, to honor the popular recipe’s origin, Massachusetts designated the chocolate chip cookie as its official state cookie. If you ever need some validation that failure can lead to success, take at look back at the beginnings of corn flakes. In 1898, W.K. Kellogg (who later became the founder of Kellogg’s) and his brother, Dr. John Harvey Kellogg, accidently produced a batch of flaked wheat berry after attempting to make granola. The Kellogg brothers then decided to experiment by flaking corn and the rest is history.

Lea & Perrins Worcestershire Sauce

The next time you slather this deliciously sweet, tangy sauce on your meal, know that without the mistake of two chemists, that meal might not be as tasty. In the early 1800’s, a man by the name of Lord Sandys appointed chemists John Lea and William Perrins to the task of recreating a recipe he had tasted in Bengal. Lea and Perrins attempted the sauce, but did not like the result, so they left the sauce in jars in a cellar. Two years later, the two stumbled across the sauce, decided to taste it and found something amazing: it actually tasted good. Today, Lea & Perrins Worcestershire Sauce is aged in a wooden cask for 18 months and is a popular dressing on meats and salads.

Yogurt

It’s believed that yogurt developed at a time when milk-producing animals became domesticated, possibly around 5,000 B.C. To transport the animal milk, the milk was often placed in sacks made from the stomachs of animals. It’s believed that the bacteria as well as the acidity from the lining of the stomachs prompted the milk to coagulate, forming the beginnings of yogurt.

Source: Fox news

 


People with Depression May Age Faster

People suffering from depression may be aging faster than other people, according to a new study from the Netherlands.

In the study of about 1,900 people who had major depressive disorders at some point during their lives, along with 500 people who had not had depression, researchers measured the length of cell structures called telomeres, which are “caps” at the end of chromosomes that protect the DNA during cell division. Normally, telomeres shorten slightly each time cells divide, and their length is thought to be an index of a cell’s aging.

The researchers found telomeres were shorter in people who had experienced depression compared with people in the control group. This suggests cellular aging in people with depression is accelerated by several years, the researchers said.

Source: Live Science