Finley Boyle: Girl Dies After Dental Procedure

A three-year-old girl has died after suffering brain damage during a visit to the dentist.

Finley Boyle visited Island Dentistry for Children in Kailua, Hawaii, with her mother Ashley on December 3 to get four root canals done.

According to court documents, she was given different drugs to sedate her but she then went into cardiac arrest.

The lawsuit claims she was left unattended for 26 minutes without CPR, leading to extensive brain damage.

Her family has said it will file a wrongful death lawsuit against the Honolulu dentist.

Family lawyer Rick Fried told KHON-TV her death was “tragic”.

He said: “I think the parents felt that Finley wouldn’t want to live. I don’t think anyone of us would.

“She didn’t know she was alive basically.”

Source: Sky news


USDA allows more meat, grains in school lunches

The Agriculture Department says it’s making permanent rules that allow schools to serve larger portions of lean meat and whole grains in school lunches and other meals.

Guidelines restricting portion size were originally intended to combat childhood obesity, but many parents complained their kids weren’t getting enough to eat. School administrators say that rules establishing maximums on grains and meats are too limiting and make it difficult to plan daily meals.

The department eliminated limits and on meats and grains on a temporary basis more than a year ago. On Thursday officials made the rule change permanent.

The change was announced by Kevin Concannon, an undersecretary for food, nutrition and consumer services.

He says the department has delivered on its promise to give school nutritionists more flexibility in meal planning.

Source: USA Today

 


China says child deaths not linked to hepatitis vaccine

Chinese health authorities said they have found no link between a hepatitis B vaccine and the deaths of nine children who had received those shots, state media said on Friday.

China has been investigating 17 deaths following inoculation with a hepatitis B vaccine, made by Shenzhen-based BioKangtai, from Dec. 13 and 31. The news alarmed many Chinese Internet users, who called on the government to make more information public.

Many Chinese people are suspicious that the government tries to cover up bad news about health problems, despite assurances of transparency. In 2003, the government initially tried to cover-up the outbreak of the SARS virus.

Nine of the cases have nothing to do with the vaccines, state news agency Xinhua cited the director of the disease control bureau of the National Health and Family Planning Commission, Yu Jingjin, as saying at a press conference.

A preliminary analysis of the eight other cases have also found no link between the deaths and the vaccines, but the cause of the deaths will be confirmed only after autopsies, Yu said.

Li Guoqing of the China Food and Drug Administration said at a press conference that no problems had been found with BioKangtai vaccines in production practices or product quality, according to Xinhua.

BioKangtai said in a statement in December that it rigorously followed safety rules but that they were testing the batches suspected of causing the deaths.

China has been beset by a series of product safety scandals over the past few years.

At least six children died in 2008 after drinking milk contaminated by the industrial chemical melamine, and there have also been reports of children dying or becoming seriously ill from faulty encephalitis, hepatitis B and rabies vaccines.

Source: Reuters


Daily routines may influence sleep quality, quantity

Maintaining a consistent daily routine may be linked to better sleep, according to a small new study.

Young adults who went to work and ate dinner around the same time every day typically slept better and woke up fewer times during the night. They also fell asleep more quickly at bedtime.

Yet the exact time people performed daily activities—say, eating dinner at 6 p.m. versus 8 p.m. —had little bearing on how well they slept.

“For the majority of sleep outcomes, we found that completing activities at a regular time better predicted sleep outcomes than the actual time of day that activities were completed,” Natalie Dautovich, a psychologist at the University of Alabama in Tuscaloosa, said. She led the study, which was published in the Journals of Gerontology: Series B.

“For example, people reported better sleep quality and fewer awakenings at night when they were consistent in the time they first went outside,” Dautovich told Reuters Health in an email.

On the other hand, for older adults, inconsistent daily schedules were sometimes linked with better sleep, the researchers found.

For instance, older people whose dinnertime varied tended to sleep longer at night. And those who started home activities or began work at different times each day fell asleep more quickly.

The study included 50 adults between the ages of 18 and 30 and another 50 between 60 and 95. Participants kept a diary of when they performed regular activities and how well they slept at night for two weeks.

Instead of opening the door to new recommendations or sleep treatments, the authors said the study best serves to create questions for future research.

Those questions include whether older adults who have more variation in their daily schedules are already healthier and more socially active—or whether it’s the variety in one’s everyday schedule that provides the activity and stimulation that help ensure good sleep, according to Dautovich.

“We know that good sleep at night is dependent in part on our drive to sleep, which is based on how active and alert we are during the day,” she said.

For that reason, being out and about during the day remains one of the best ways to maximize the chances of a solid night of shut-eye.

“Greater activity and levels of alertness during the day increase our need to sleep at night,” Dautovich said.

Source: GMA network


Women may skip radiation therapy over child care concerns

Child care issues may keep breast cancer patients from getting the treatments they need, a new study suggests.

Mothers with young children were more likely to skip recommended radiation treatments after breast cancer surgery because of worries about the time involved, researchers found.

In particular, women who had a breast tumor removed were less likely to undergo radiation therapy afterwards if they had kids age seven or younger at home.About 81 per cent of women surveyed in the study who had younger kids received radiation therapy. The rates of radiation therapy for women with older kids or none at all ranged between 84 and 87 per cent.

Put another way, one in five women with young kids in the study skipped potentially life-saving post-surgery treatment, said Ya-Chen Tina Shih, an economist and associate professor of medicine at the University of Chicago in Illinois who co-led the study.

“We were surprised because women in the younger age range have the longest life expectancy, so we expected to see a higher compliance rate among them,” she told Reuters Health.

“Women may think, ‘I really need to take care of the kids at home,’ and they may act on what they believe is most important at that time,” Shih said.

“But they may not be aware of how important radiation therapy is.”

Women who have “lumpectomy” surgery to remove a breast tumor – the researchers did not include patients who had mastectomies – are usually advised to follow up with radiation therapy, which requires a serious time commitment. The radiation treatments take up to an hour, five days a week, for up to seven weeks, the researchers report.

“Many have hypothesized that young children might be a barrier for younger women, but this paper is the first to demonstrate that,” wrote Dr. Nancy Keating in an email to Reuters Health.

Keating, an associate professor at Harvard Medical School’s Department of Health Care Policy in Boston, was not involved in the new study.

“It suggests there is a modifiable barrier to improving care: providing child care,” Keating said.

For their study, Shih and her team looked at 21,008 patients who filed breast cancer surgery claims between 2004 and 2009 with employer-sponsored insurance.

From the data provided by Truven Health Analytics, researchers knew how many kids – dependents – were in a woman’s household.

The team found additional barriers to radiation therapy. Patients who enrolled in HMO plans, or PPO plans with fixed reimbursement amounts, were less likely to follow through with the treatment. If a patient had to travel far for the surgery itself, then she was also less likely to get radiation.

But this study’s biggest contribution is highlighting how childcare may play a role, Keating said.

Women, like those in the study, who chose breast-conserving surgery and not a mastectomy, “may not understand that the surgery is equivalent to mastectomy in terms of outcomes if women also get the radiation,” Keating wrote.

Shih pointed out that one weakness in her team’s report, published in the Journal of the National Cancer Institute, was that they did not talk to the patients themselves to record their reasons for not getting radiation therapy.

The study shows an association between the age of a woman’s children and her likelihood of opting out of radiation, but does not prove cause and effect.

Future studies could also investigate the rates of radiation therapy among women without insurance, or with less generous benefits, Shih said.

But for now, “the person in charge of a patient’s entire cancer care needs to make sure that they know if a patient has younger kids,” Shih said.

“If friends and family can make a commitment to help with the patient’s child care needs for a month or two – that could make a big difference,” she said.

The findings “suggest that providers, like hospitals, physician groups or health systems, could potentially help by providing assistance with child care,” Keating said.

Source: Khaleej times


Scientists discover new way of overcoming human stem cell rejection

Human embryonic stem cells have the capacity to differentiate into a variety of cell types, making them a valuable source of transplantable tissue for the treatment of numerous diseases, such as Parkinson’s disease and diabetes.

But there’s one major issue: Embryonic stem cells are often rejected by the human immune system.

Now, researchers from the University of California San Diego may have found an effective way to prevent this rejection in humans. Utilizing a novel humanized mouse model, the scientists have revealed a unique combination of immune suppressing molecules that stop the immune system from attacking the injected stem cells – without shutting the system down completely.

This discovery could ultimately help resolve some of the major problems currently limiting the use of embryonic stem cells for certain conditions, paving the way for the development of more effective human stem cell therapies.

“This is a generic way of immune suppression, so it could potentially be applied not just for stem cells therapies, but for organ transplants as well,” Yang Xu, a professor of biology at UC San Diego and lead author of the study, told FoxNews.com. “It can be very broad.”

Embryonic stem cells are different from the other cells in a patient’s body, making them “allogenic.” This means the immune system will recognize them as foreign agents and attack them.

One way of overcoming this rejection problem is to give patients immunosuppressant drugs, which suppress the entire immune system. While short term use of immunosuppressants has been successful for many organ transplants, embryonic stem cell therapies for chronic diseases require long term use of these drugs – which can often be very toxic and increase the risk of cancer.

“In order for the patient to really use this therapy, they have to decide: Do they want a lifelong use of immunosuppressant drugs, or are they willing to live with the symptoms of their disease,” Xu said.

Source: news.nom


Woman’s tragic death witnessed by family on laptop

A nurse in a Michigan hospital kissed the patient’s forehead. More than 6,000 miles away, Sanaz Nezami’s family in Iran watched on a laptop computer and wept.

Nezami, a vibrant 27-year-old woman who could speak three languages, wanted to pursue an advanced degree in engineering at Michigan Technological University. Instead, she was brain dead just a few weeks after unpacking her bags, the victim of a fatal beating by her new husband, according to police.

Technology allowed family in Iran to watch her final hours. The family’s faith in the hospital staff led to consent for an extraordinary donation: Nezami’s heart, lungs and other life-saving organs were transplanted to seven people in the U.S., a remarkable gift that occurs in less than 1% of all cases.

“We wanted God to perform a miracle and bring Sanaz back to life,” her sister, Sara Nezami, said in a phone interview from Tehran. “But this is a miracle. Sanaz gave her life in order to give life.”

A nurse who took care of Sanaz Nezami said the experience was “eye-opening” for hospital staff.

“The family was willing to trust us to know she wasn’t coming back,” Kim Grutt said.

In August, Nezami married Nima Nassiri in Turkey and lived with him temporarily in the Los Angeles area, where he was born and raised. Her sister said the two met over the Internet.

Nezami, a native of Tehran, had a bachelor’s degree in engineering and a master’s in French translation. She wanted a doctorate degree in environmental engineering.

On Dec. 7, she asked her sister to proofread some English-to-Persian translation she was doing on the side.

“I was shocked,” Sara Nezami said. “Sanaz was a very precise girl, but she omitted some lines. I asked, ‘Are you OK?’ She told me there was no problem.”

The next day, Sanaz Nezami was rushed to a hospital with severe head injuries and was transferred to Marquette General Hospital. Police believe she was assaulted by her husband, who has been charged with second-degree murder. His attorney, David Gemignani, declined to comment.

“Her brain was so swollen and so damaged, there was no longer any blood flow,” explained Gail Brandly, who supervises nurses at the hospital.

No one knew anything about Nezami, so Brandly ran her name through Google. Suddenly, the stranger who couldn’t speak for herself came alive through a résumé posted online.

After about 24 hours, the hospital reached relatives in Iran. Immediate travel to the U.S. was impractical due to visa requirements, so a laptop was set up so the family could see Nezami on life support and talk to nurses and doctors over Yahoo Messenger.

“It isn’t something we’ve done in the past. It’s not every day we’re dealing with family members so far-flung,” said Dave Edwards, spokesman for the hospital.

At one point, Grutt was asked to stroke Nezami’s head and kiss her forehead.

Nezami was buried Dec. 18 in a local cemetery. As a light snow fell, the hospital’s chaplain, the Rev. Leon Jarvis, read Muslim prayers over the casket while about 20 people, mostly nurses and others who cared for her, watched.

Source: detroit free press


Medicaid expansion increased visits to emergency rooms

People newly enrolled in a health insurance program for the poor were more likely to visit the emergency department for care than people who remained uninsured, Boston-area researchers have found, providing the best evidence to date that the national Medicaid expansion that began this week is unlikely to lead to a decline in costly emergency services.

The study was published online Thursday by the journal Science, just as millions of Americans have become newly eligible for Medicaid coverage under the Affordable Care Act. Some politicians have suggested that people who were uninsured and didn’t have a regular doctor or put off basic treatment until their condition became serious, would, once they had coverage, get the primary care they needed to avoid trips to the emergency department.

Previous research on what happened to ER usage in Massachusetts, which expanded its Medicaid program and mandated that most residents have health insurance in 2006, have reached conflicting conclusions. But the new study, of about 25,000 low-income adults randomly selected in 2008 to enroll in Oregon’s Medicaid program, found that the newly insured increased their use of all types of medical care, including prescription drugs, hospital stays, and outpatient visits. Emergency department visits were no exception.

Over an 18-month period, about 42 percent of the new Medicaid enrollees visited the emergency department. In the same period, about 35 percent of those who did not receive Medicaid visited the emergency department.

“Basic economic theory is, if you lower the price, people use it more,” said Amy Finkelstein, a Massachusetts Institute of Technology economist and a senior author on the paper.

It was not a foregone conclusion in this case, however, that reducing the cost of an emergency room visit would increase use, she said, because the cost of a visit to a primary care doctor and of preventive services that may have helped them avoid the emergency room also decreased with insurance coverage.

Yet, emergency department use among those on Medicaid increased during businesses hours, nights, and weekends. While there was no increase in visits classified as non-preventable emergencies, there was an increase for visits deemed preventable or treatable by a primary care doctor.

A 2011 study found that overall emergency department visits increased in Massachusetts in the two years after the state expanded insurance coverage under the 2006 state health care law, though visits for “low severity” problems declined slightly. Dr. Peter Smulowitz, an emergency physician at Beth Israel Deaconess Medical Center and lead author on that study, said he and colleagues have more recently reviewed emergency department use across Massachusetts and found a small increase in pockets of the state that had seen the largest gains in insurance coverage. The study is pending publication.

Data published in the New England Journal of Medicine in 2011, however, found that ER usage was already increasing in Massachusetts and nearby states before the expansion of health insurance coverage here, and that the law did not change the trend in Massachusetts when compared to the other states.

The Oregon study is unique in that it is a randomized controlled study, considered the gold standard in medical research but rarely feasible in health policy research. The state of Oregon created a valuable study scenario when, because the state had money only for a small expansion of the program, it held a lottery for Medicaid coverage, providing insurance to some people and leaving others uninsured.

Past work by principal investigators Finkelstein and Katherine Baicker, a professor of health economics at Harvard School of Public Health, and their colleagues at the National Bureau of Economic Research in Cambridge has found that the lottery winners were more likely to report feeling better about their mental and physical health and had less financial strain, including fewer bills sent to collection. But there was no improvement in key health factors, such as blood pressure or blood sugar levels, as compared with the uninsured.

With the latest study, Baicker said, the body of research out of Oregon has disproved both the worst and best predictions for Medicaid — that it is an expensive program that does little to improve access to care and overall health, or alternatively, that it is a money-saving program that clearly improves health. The results are far more nuanced.

“Policymakers should make decisions based on this evidence that the program has real costs. It’s not free,” she said. “And, it has real benefits. Beneficiaries are clearly better off.”

Source: the boston globe


Jahi McMath family, hospital to meet for settlement talks

A federal magistrate has ordered settlement talks between attorneys for Children’s Hospital Oakland and the family of a 13-year-old girl who has been declared brain dead.

U.S. Magistrate Donna Ryu will meet in her Oakland courtroom Friday with both sides in hopes of brokering a deal in the ongoing legal fight over Jahi McMath. A separate hearing has been scheduled Friday before Judge Evelio Grillo of Alameda County Superior Court in Oakland.

Jahi’s family has accused the hospital of denying the girl a tracheostomy tube that is required to transfer her to another site, as well as withholding the insertion of a feeding tube that will provide her nutrition. They maintain that she is not dead because her heart is still beating and she is hooked up to a ventilator.

Hospital representatives have said that they’ve never objected to the girl receiving a tracheostomy but would not allow the procedure done in its hospital or performed by its staff because of the ethical and legal issues related to operating on a deceased person.

The hospital’s doctors declared Jahi dead on Dec. 12, three days after she underwent a tonsillectomy that resulted in complications.

The hospital would arrange for Jahi to be moved to another site for the procedure, or for long-term care, but has not heard from any facility, doctor or medical transport service regarding her case, hospital spokesman Sam Singer said.

Christopher Dolan, attorney for Jahi’s family, has filed requests in three separate courts seeking orders to force the hospital to insert tracheostomy and feeding tubes, but judges have declined to do so.

In court papers filed in federal court Thursday, Dolan again asked for an order for the tubes to be inserted.

“At this point, Jahi has not had nutrition for nearly three weeks,” he wrote. “She is in desperate need of a tracheostomy tube and a gastric tube.. This court should grant plaintiff the relief to allow for Jahi’s transport.”

Grillo has issued a restraining order that prevents the hospital from disconnecting Jahi from a ventilator until at least 5 p.m. Tuesday.

At 1 p.m. on Tuesday, U.S. District Judge Saundra Brown Armstrong in Oakland is expected to hear arguments about possible violations of Jahi’s civil rights, and the rights of families – not doctors, lawyers or politicians – to determine a loved one’s death, based on their religious or personal beliefs.

Source: SF gate


Low oxygen bad for breast cancer patients

Breast cancer cells, when exposed to low oxygen conditions, trigger the production of two proteins that make the cancer cells spread fast — making the patient’s condition worse, a new paper has contended.

Researchers at The Johns Hopkins University reached the conclusion that low oxygen conditions, frequently present in breast cancers, facilitates the production of RhoA and ROCK1 proteins that, in turn, endow the cancer cells with the ability to move.

“High levels of RhoA and ROCK1 were known to worsen outcomes for breast cancer patients by endowing cancer cells with the ability to move, but the trigger for their production was a mystery,” said Gregg Semenza, Professor of Medicine at The Johns Hopkins University.

The researchers found that women with high levels of RhoA or ROCK1, and especially those women with high levels of both, were more likely to die of breast cancer than those with low levels.

“We now know that the production of these proteins increases dramatically when breast cancer cells are exposed to low oxygen conditions,” said the paper, published in the journal Proceedings of the National Academy of Sciences.

With the multiplying of tumour cells, the interior of the tumour begins to run out of oxygen simply because they are not being supplied by blood vessels.

“The lack of oxygen activates the hypoxia-inducible factors, which are master control proteins that switch on many genes that help cells adapt to the scarcity of oxygen,” explained Semenza.

Hypoxia refers to a condition in which the body or a part of the body is deprived of adequate supply of oxygen.

Hypoxia-inducible factors also turn on genes that help cancer cells escape from the oxygen-starved tumour by invading blood vessels, through which they spread to other parts of the body, the paper added.

Here is a breather, though.

“We have successfully decreased the mobility of breast cancer cells in the lab by using genetic tricks to knock the hypoxia-inducible factors down,” said Daniele Gilkes, lead author of the paper.

“Now that we understand the mechanism at play, we hope that clinical trials will be performed to test whether drugs that inhibit hypoxia-inducible factors will have the double effect of blocking production of RhoA and ROCK1 and preventing metastases in women with breast cancer,” Gilkes added.

Source: Pak tribune