Drug-resistant TB spreading fast in Russia

scientists have found that tuberculosis strains in Russia carry mutations that not only make them resistant to antibiotics but also help them spread more effectively.

The latest study of TB cases in Russia indicates that rampant drug resistance may not be the only explanation for the TB rise in the region – biological factors also play a major role in it.

Researchers at Queen Mary University of London analysed 1,000 genomes from different TB isolates – the largest whole-genome study of a single bacterial species so far.

This enabled the team to identify previously unknown mutations linked to antibiotic resistance, as well as “compensatory mutations” that improve the ability of drug-resistant TB to spread.

Nearly half of the TB isolates were multi-drug resistant, which means that they were impervious to the two common first-line antibiotics that cure most TB infections.

Sixteen percent of these isolates also harboured mutations that made them impervious to “second-line” drugs.

These infections are more expensive to treat and patients who receive ineffective drugs are more likely to spread TB, said the research published in the journal Nature Genetics.

TB, which is caused by the bacterium Mycobacterium tuberculosis, exploded in Russia and other former Soviet nations in the early 1990s, after the collapse of the Soviet Union and its health system.

“It certainly adds an extra layer of worry, because one had assumed if you could solve ‘programmatic’ weaknesses, you would solve the problem of the drug-resistant TB,” stressed Francis Drobniewski, a microbiologist at Queen Mary University.

“Although we know the general story of TB drug resistance in Russia, these new findings are still shocking,” added Christopher Dye, an epidemiologist at the World Health Organisation (WHO) in Geneva.

According to Megan Murray, an epidemiologist at the Harvard School of Public Health in Boston, Massachusetts, the worst scenario is that the organisms are developing resistance, compensating for it, and evolving into something that’s new and different, that’s much less treatable.

Source: Sify

 


Healthy lifestyle to improve oral health in diabetics

Diabetics, who are at a higher risk of suffering from oral health problems, can avoid these by adopting a healthy lifestyle.

Researchers at the University of Copenhagen have helped a large group of diabetics to markedly improve their oral health through health coaching.

“Diabetics are at a higher risk of suffering oral health issues like periodontitis and caries and other problems like dry mouth, fungal infections and poor wound healing,” said Ayse Basak Cinar, assistant professor at department of odontology at the university.

In all, 186 patients with type 2 diabetes participated in the study done in Turkey – the first in the world – to demonstrate the role of health coaching in improving dental health.

The patients with diabetes were divided into two groups.

One group was given traditional health information, for example a brochure on good dental hygiene.

The other group was offered motivational health coaching in the form of 3-6 sessions over a six-month period, focusing on diet, stress management and dental care, said the research published in the journal Clinical Oral Investigations.

“In patients who were given personal health coaching, biological markers for periodontitis – also known as loose teeth disease – were reduced by as much as 50 percent over a six-month period,” the research noted.

“The patients in the trial group saw a significant decline in long-range blood sugar levels, whereas figures for the control group were unchanged,” said.

“Health coaching is a resource-intensive intervention. However, dishing out brochures to patients with diabetes and thinking that this would help is also a costly approach for the society,” he added.

Source; Business standard


New drug may stop spread of breast cancer

Researchers have identified a new compound that completely halts the spread of metastatic breast cancer in mice.

The vast majority of deaths from cancer result from its progressive spread to vital organs such as the brain and lungs – a process known as metastasis.

In a recent series of studies researchers identified a previously unknown critical role for a potential cancer causing gene, Bcl3, in metastatic breast cancer.

“We showed that suppressing this gene reduced the spread of cancer by more than 80 per cent,” said Dr Richard Clarkson from Cardiff University’s European Cancer Stem Cell Research Institute.

“Our next goal was to then find a way to suppress Bcl3 pharmacologically. Despite great improvements in therapy of early stage breast cancer, the current therapeutic options for patients with late stage metastatic disease are limited.

“There is therefore a clear unmet clinical need to identify new drugs to reverse or at least to slow down disease progression,” he added.

Clarkson and his team joined up with researchers Dr Andrea Brancale and Dr Andrew Westwell from the Cardiff University School of Pharmacy and Pharmaceutical Sciences, to develop small chemical inhibitors of the Bcl3 gene.

Computer aided modelling of how the Bcl3 gene functions inside the cell allowed the group to identify a pocket on the surface of Bcl3 essential for its function.
By screening a virtual compound library for chemicals that could fit inside this pocket, using state-of-the-art computer software, they identified a drug candidate that potently inhibits Bcl3.

The compound was then trialled on mice with metastatic disease. The resulting effect was that the drug completely inhibited the development of the mice’s metastatic tumours.
Researchers are now working to conduct clinical trials of the compound. The aim is to develop a therapeutic agent capable of blocking metastatic disease in breast cancer and a variety of tumour types.

Source: Business Standard


Helping Smokers Quit, or Not Start in the First Place

“Even 50 years after the first surgeon general’s report on smoking and health, we’re still finding out new ways that tobacco kills and maims people,” Dr. Thomas Frieden, director of the Centers for Disease Control and Prevention, recently told me. “It’s astonishing how bad it is.”

Dr. Frieden and public health specialists everywhere are seeking better ways to help the 44 million Americans who still smoke to quit and to keep young people from getting hooked on cigarettes. “Fewer than 2 percent of doctors smoke. Why can’t we get to that rate in society as a whole?” he wondered.

One reason: Smoking rates are highest among the poor, poorly educated and people with mental illness, populations hard to reach with educational messages and quit-smoking aids.

But when I mentioned to Dr. Frieden, a former New York City health commissioner, that the city’s streets are filled with young adult smokers who appear to be well educated and well dressed, he said television seems to have had an outsize influence.

Focus groups of white girls in New York private schools have suggested a “Sex in the City” effect, he said: Girls think smoking makes them look sexy. In the last two years, middle-aged men, too, have begun smoking in increasing numbers after a half-century decline. Dr. Frieden cited “Mad Men,” the popular TV series featuring admen in the early 1960s, when well over half of American men smoked.

Dr. Frieden said that an antismoking effort begun in 2008 by the World Health Organization “can make a huge difference in curbing smoking, and we should fully implement what we know works.” The program is called Mpower:

M stands for monitoring tobacco use and the effectiveness of prevention programs like antismoking videos on YouTube.

P for protecting people from secondhand smoke. Half the country still lacks laws mandating smoke-free public places. The latest national health survey found that about half of children from nonsmoking households have metabolites of tobacco in their blood, Dr. Frieden said.

O for offering help to the 70 percent of smokers who say they would like to quit. “Tobacco use remains egregiously undertreated in health care settings,” Dr. Helene M. Cole, associate editor of JAMA, The Journal of the American Medical Association, and Dr. Michael C. Fiore, a professor of medicine at the University of Wisconsin, wrote this month in the journal.

Medical aids for quitting smoking, which can triple the likelihood of success, should become available, without a co-pay, to many more people under the Affordable Care Act, Dr. Frieden said.

W for warning about smoking hazards through larger and more graphic messages on cigarette packs and paid advertising on radio and television.

E for enforcing bans on tobacco marketing, advertising, promotion and sponsorships. In bodegas throughout the country, Dr. Frieden said, “tobacco ads are used as wallpaper.” Smoking is freely depicted in movies and popular TV shows.

R for raising taxes, which studies have shown is the single most effective way to reduce smoking in the population, especially among teens.

“A higher cigarette tax is not a regressive tax, because it would help poor people even more than the well-to-do,” Dr. Frieden noted. President Obama has proposed an additional 94-cent-per-pack tax on cigarettes, which would yield $80 billion to fund universal prekindergarten.

Smokers ready to quit can choose from among a cornucopia of aids as wide-ranging as nicotine substitutes, low-dose antidepressants, hypnosis and acupuncture. While none by itself has a high rate of success, different methods have proved effective for different people. Many former smokers required several attempts before they managed to quit for good.

But quitting smoking does not necessarily require assistance. As two public health specialists, Andrea L. Smith and Simon Chapman at the University of Sydney in Australia, have pointed out, “The vast majority of quitters do so unaided.” A Gallup Poll conducted last year in the United States found that “only 8 percent of ex-smokers attributed their success to [nicotine replacement therapy] patches, gum or prescribed drugs,” these experts noted. “In contrast, 48 percent attributed their success to quitting ‘cold turkey’ and 8 percent to willpower, commitment or ‘mind over matter’.”

They added, “For many smokers, having a reason to quit (a why) was more important than having a method to quit (a how).”

For my husband, who smoked a pack a day for 50 years, the “why” was his distress at seeing two beautiful young nieces smoking; he made a pact with them to quit if they would, and he followed through.

Techniques that can help people trying to quit when troubled by the urge to smoke include waiting 10 minutes and distracting yourself; avoiding situations you associate with smoking, at least until you have become a committed ex-smoker; using stress reducers like physical activity, yoga, deep breathing, muscle relaxation and self-hypnosis; seeking moral support from a nonsmoking friend, family member or online stop-smoking program; and oral distractions like chewing sugarless gum or raw vegetables.

Electronic cigarettes are being promoted by some as a way to resist the real thing. E-cigarettes, invented in 2003 by a Chinese pharmacist, contain liquid nicotine that is heated to produce a vapor, not smoke. More than 200 brands are now on the market; they combine nicotine with flavorings like chocolate and tobacco.

But their contents are not regulated, and their long-term safety has not been established. In one study, 30 percent were found to produce known carcinogens. Dr. Frieden said that while e-cigarettes “have the potential to help some people quit,” the method would backfire “if it gets kids to start smoking, gets smokers who would have quit to continue to smoke, gets ex-smokers to go back to smoking, or re-glamorizes smoking.”

Nearly two million children in American middle and high schools have already used e-cigarettes, Dr. Frieden said. In an editorial in the Canadian Medical Association Journal last year, Dr. Matthew B. Stanbrook, an assistant professor of medicine at the University of Toronto, suggested that fruit-flavored e-cigarettes and endorsements by movie stars could lure teens who would not otherwise smoke into acquiring a nicotine habit.

A survey in 2011 of 75,643 South Korean youths in grades 7 through 12 by researchers at the University of California, San Francisco, revealed that four of five e-cigarette users also smoked tobacco. It could happen here: Stanton A. Glantz, the study’s senior author and a professor of medicine at the university, described e-cigarettes as “a new route to nicotine addiction for kids.”

Source: New York Times


Beijing’s air would be step up for smoggy Delhi

In mid-January, air pollution in Beijing was so bad that the government issued urgent health warnings and closed four major highways, prompting the panicked buying of air filters and donning of face masks. But in New Delhi, where pea-soup smog created what was by some measurements even more dangerous air, there were few signs of alarm in the country’s boisterous news media, or on its effervescent Twittersphere.

Despite Beijing’s widespread reputation as having some of the most polluted air of any major city in the world, an examination of daily pollution figures collected from both cities suggests that New Delhi’s air is more laden with dangerous small particles of pollution more often than Beijing’s. Lately, a very bad air day in Beijing is about an average one in New Delhi.

The U.S. Embassy in Beijing sent out warnings in mid-January, when a measure of harmful fine particulate matter known as PM2.5 for the first time this year went above 500, in the upper reaches of the measurement scale. This refers to particulate matter less than 2.5 micrometers in diameter, which are believed to pose the greatest health risk because they penetrate deeply into lungs.

But for the first three weeks of this year, New Delhi’s average daily peak reading of fine particulate matter from Punjabi Bagh, a monitor whose readings are often below those of other city and independent monitors, was 473, more than twice as high as the same average in Beijing of 227. By the time Beijing had its first pollution breach past 500 on the night of Jan. 15, Delhi had already had eight such days. Indeed, only once in three weeks did New Delhi’s daily peak value of fine particles fall below 300, a level more than 12 times the exposure limit recommended by the World Health Organization.

“It’s always puzzled me that the focus is always on China and not India,” said Angel Hsu, director of the environmental performance measurement program at the Yale Center for Environmental Law and Policy. “China has realized that it can’t hide behind its usual opacity, whereas India gets no pressure to release better data. So there simply isn’t good public data on India like there is for China.”

Experts have long known that India’s air is among the worst in the world. A recent analysis by Yale researchers found that seven of the 10 countries with the worst air pollution exposures are in South Asia. And evidence is mounting that Indians pay a higher price for air pollution than almost anyone in the world. A recent study showed that Indians have the world’s weakest lungs, with far less capacity than Chinese lungs. Researchers are beginning to suspect that India’s unusual mix of polluted air, poor sanitation and contaminated water may make the country among the most dangerous in the world for lungs.

India has the world’s highest death rate because of chronic respiratory diseases, and it has more deaths from asthma than any other nation, according to the World Health Organization. A recent study found that half of all visits to doctors in India are for respiratory problems, according to Sundeep Salvi, director of the Chest Research Foundation in Pune.

Clean Air Asia, an advocacy group, found that another common measure of pollution known as PM10, for particulate matter less than 10 micrometers in diameter, averaged 117 in Beijing in a six-month period in 2011. In New Delhi, the Center for Science and Environment used government data and found that an average measure of PM10 in 2011 was 281, nearly 2 1/2 times higher.

Perhaps most worrisome, Delhi’s peak daily fine particle pollution levels are 44 percent higher this year than they were last year, when they averaged 328 over the first three weeks of the year. Fine particle pollution has been strongly linked with premature death, heart attacks, strokes and heart failure. In October, the World Health Organization declared that it caused lung cancer.

The U.S. Embassy in Beijing posts on Twitter the readings of its air monitor, helping to spur wide awareness of the problem. The readings have more than 35,000 followers. The United States does not release similar readings from its New Delhi embassy, saying the Indian government releases its own figures.

In China, concerns about air quality have transfixed many urban residents, and some government officials say curbing the pollution is a priority.

But in India, Delhi’s newly elected regional government did not mention air pollution among its 18 priorities, and India’s environment minister quit in December amid widespread criticism that she was delaying crucial industrial projects. Her replacement, the government’s petroleum minister, almost immediately approved several projects that could add considerably to pollution. India and China resisted pollution limits in global climate talks in Warsaw in November.

Frank Hammes, chief executive of IQAir, a Swiss-based maker of air filters, said his company’s sales were hundreds of times higher in China than in India.

“In China, people are extremely concerned about the air, especially around small children,” Hammes said. “Why there’s not the same concern in India is puzzling.”

In multiple interviews, Delhiites expressed a mixture of unawareness and despair about the city’s pollution levels. “I don’t think pollution is a major concern for Delhi,” said Akanksha Singh, a 20-year-old engineering student who lives on Delhi’s outskirts in Ghaziabad, adding that he felt that Delhi’s pollution problems were not nearly as bad as those of surrounding towns.

In 1998, India’s Supreme Court ordered that Delhi’s taxis, three-wheelers and buses be converted to compressed natural gas, but the resulting improvements in air quality were short-lived as cars have flooded the roads. In the 1970s, Delhi had about 800,000 vehicles; now it has 7.5 million, with 1,400 more added daily.

“Now the air is far worse than it ever was,” said Anumita Roy Chowdhury, executive director of the Center for Science and Environment.

Indians’ relatively poor lung function has long been recognized, but researchers assumed for years that the difference was genetic.

Then a 2010 study found that the children of Indian immigrants who were born and raised in the United States had far better lung function than those born and raised in India.

“It’s not genetics; it’s mostly the environment,” said MyLinh Duong, an assistant professor of respirology at McMaster University in Hamilton, Ontario.

In a study published in October, Duong compared lung tests taken in 38,517 healthy nonsmokers from 17 countries who were matched by height, age and sex. Indians’ lung function was by far the lowest among those tested.

All of this has led some wealthy Indians to consider leaving.

Annat Jain, a private equity investor who returned to India in 2001 after spending 12 years in the United States, said his father had died last year of heart failure worsened by breathing problems. Now his 4-year-old daughter must be given twice-daily breathing treatments.

“But whenever we leave the country, everyone goes back to breathing normally,” he said. “It’s something my wife and I talk about constantly.”

Source: Ndtv news


Pepsi One and Potential Cancer-Causing Chemical

Pepsi One has higher levels of a potential cancer-causing chemical than other soft drinks, according to a study released Thursday by Consumer Reports magazine.

Researchers looked at levels of a chemical called 4-methylimidazole (4-MeI), which is found in artificial caramel coloring used in soft drinks. There are no federal limits on the chemical’s use, but California requires warning labels on foods or beverages that expose consumers to more than 29 micrograms of 4-MeI a day, the Los Angeles Times reported.

The Consumer Reports study said that 12-ounce cans of the low-calorie soft drink Pepsi One bought in California contained as much as 43.5 micrograms of 4-MeI, and that a nonalcoholic malt beverage called Malta Goya had as much as 352.5 micrograms of the chemical, the Times reported.

In contrast, cans of Coca-Cola and Dr. Pepper contained 4.3 micrograms and 10.1 micrograms, respectively, of 4-MeI, the Times said.

A person would have to drink more than 1,000 cans of soda a day to reach the levels of 4-MeI linking the chemical and cancer in rodents, according to the U.S. Food and Drug Administration, the newspaper reported.

In 2012, both Coca-Cola Co. and PepsiCo Inc. promised to reduce the amount of 4-MeI in their drinks, the newspaper said.

“We are concerned about both the levels of 4-MeI we found in many of the soft drinks tested and the variations observed among brands, especially given the widespread consumption of these types of beverages,” said Urvashi Rangan, a toxicologist and executive director of the Consumer Reports Food Safety and Sustainability Center, the Times reported.

Pepsi disputed the study findings. The soda maker said levels of 4-MeI in its drinks did not equal 29 micrograms a day because “the average amount of diet soda consumed by those who drink it is approximately 100 [milliliters] per day, or less than a third of a 12 [ounce] can,” the Times reported. Goya Foods Inc. refused comment, the newspaper said.

Consumer Reports has asked the California attorney general to investigate whether Pepsi One and Malta Goya should have warning labels, the Times reported.

Source: Web md


Biofuel Crops ‘May Amplify Mosquito-Borne Disease’

The expansion of the some biofuel crops may unwittingly increase the risk of mosquito-borne disease by altering the insects’ life cycle, a study suggests.

The so-called first-generation biofuel crops, most notably maize, are increasingly being replaced by second-generation biofuel crops, such as perennial grasses, which require less energy, water, fertilisers and pesticides to thrive.

Yet ecological changes brought about by large-scale biofuel farming may alter the transmission of vector-borne diseases, by affecting vector behaviour, survival and abundance, for example.

In the paper published in this month’s edition of Global Change Biology – Bioenergy, researchers from the University of Illinois, United States, looked at the egg-laying behaviour of Aedes aegypti and Aedes albopictus, in water that contained leaves of different types of biofuel crops in laboratory experiments, as may happen in the field.

They show that leaves from different types of biofuel crops can affect the chemical properties of the water in which mosquitoes lay their eggs, as well as the mosquitoes’ preference for where to lay eggs and the survival of those eggs.

The researchers show, for example, that more eggs reached adulthood when they were laid in water that was infused with leaf material from the second-generation biofuel crops, switchgrass and Miscanthus, than that infused with maize leaves.

“It may appear that the transition to second-generation biofuel crops could increase mosquito production and consequently the risk of mosquito-borne disease,” they write.

But they add that these crops are also expected to improve wildlife diversity, which may reduce infection prevalence by redirecting mosquito bites to other hosts.

“We recommend further studies to explore the pathways by which these crops are likely to influence disease risk so that any potential negative impacts on human health can be identified and mitigated,” they conclude.

Nick Hewitt, an atmospheric chemist at Lancaster University, United Kingdom, tells SciDev.Net: “Large-scale land-use change is bound to have unintended consequences. In this study, an important unintended second-order consequence of biofuel crop production is identified: changes in water chemistry may change mosquito breeding patterns and hence may have effects on the prevalence of mosquito-borne diseases.”

The study, he says, highlights the “critical need for full life-cycle and environmental impact assessments of crops and agricultural practices”.

Source: All Africa


Food addicts: New study measures out-of-control eating .

While “food addiction” is somewhat controversial, a new study is shedding some light on women who may actually fit the profile of an addict, rather than simply liking chips and dip.

Research released this week online in the American Journal of Clinical Nutrition looked at food addiction among 134,000 middle-aged and older women, all of whom participated in the large-scale Nurses’ Health Study. Nearly six percent met the criteria for food addiction as established by the Yale Food Addiction Scale, which was developed in 2009 and validated in numerous trials.

Middle-aged women fared the worst. Slightly more than 8 percent of women ages 45 to 64 could be considered food addicts, while 3 percent of older women met the criteria.

The Food Addiction Scale asks questions such as: “I find that when I start eating certain foods, I end up eating much more than planned” and “I find myself continuing to consume certain foods even though I am no longer hungry”.

“We’re starting to see the patterns with food addictions that we see in other addictions, and one of them is that younger people have more addiction problems,” says addiction specialist Ashley Gearhardt, assistant professor of psychology at the University of Michigan, Ann Arbor, who worked on the study along with researchers from the Harvard School of Public Health.

The women who met criteria for food addiction were also more likely to be not married and not currently smoking. Researchers suspect that former smokers have simply traded the nicotine addiction for a food addiction, a process called addiction transference.

Although addiction was strongly associated with a higher body mass index (BMI), the data also show that you can be an average-weight woman or even underweight and have a negative relationship with food. Geography seems to matter, too. Women from the eastern United States seem to have fewer problems with food addiction than those from the South or Midwest, although researchers don’t know why.

The foods of choice for these women were so-called “hyper-palatable” treats that are high in fat, sugar, salt and processing. These foods seem to trigger the brain’s pleasure and reward centers through increases in the transmission of the “feel good” chemical, dopamine.

“The major narrative with every addiction is that people have no willpower,” says Gearhardt, who was one of the developers of the Yale Food Addiction Scale. “We know that’s not true, so we are trying to better understand if there are some foods that can hijack the system, given the right vulnerabilities in a person, and this study helps us identify those individuals.”

Because the researchers looked at a large population, the data may have important clinical implications. “We are finally getting at a distinct subset of individuals who are struggling in a way that looks like substance abuse more than anything else,” says Marlene Schwartz, director of the Rudd Center for Food Policy and Obesity at Yale University, who was not involved in the study. “Saying eat more vegetables and exercise more won’t work with people who are struggling like this.”

Source: NBC news


Making music videos ‘helps young cancer patients cope’

Music therapy can help teenagers and young people cope better when faced with treatment for cancer, a study in Cancer journal suggests.

American researchers followed the experiences of a group of patients aged 11-24 as they produced a music video over three weeks.

They found the patients gained resilience and improved relationships with family and friends.

All the patients were undergoing high-risk stem-cell transplant treatments.

To produce their music videos, the young patients were asked to write song lyrics, record sounds and collect video images to create their story.

They were guided by a qualified music therapist who helped the patients identify what was important to them and how to communicate their ideas.

When completed, the videos were shared with family and friends through “premieres”.

Positive effect
After the sessions, the researchers found that the group that made music videos reported feeling more resilient and better able to cope with their treatment than another group not offered music therapy.

Also, 100 days after treatment, the same group said they felt communication within their families was better and they were more connected with friends.

These are among several protective factors identified by researchers that they say help teenagers and young adults to cope in the face of cancer treatments.

Lead study author Dr Joan Haase, of Indiana University School of Nursing, said: “These protective factors influence the ways adolescents and young adults cope, gain hope and find meaning in the midst of their cancer journey.

“Adolescents and young people who are resilient have the ability to rise above their illness, gain a sense of mastery and confidence in how they have dealt with their cancer, and demonstrate a desire to reach out and help others.”

When researchers interviewed the patients’ parents, they found that the videos also gave them useful insights into their children’s cancer experiences.

Feel connected’
Sheri Robb, a music therapist who worked on the study, explained why music was particularly good at encouraging young people to engage.

She said: “When everything else is so uncertain, songs that are familiar to them are meaningful and make them feel connected.”

Cancer Research UK says music therapy can help people with cancer reduce their anxiety and improve their quality of life. It can also help to reduce some cancer symptoms and side-effects of treatment – but it cannot cure, treat or prevent any type of disease, including cancer.

Previous studies looking at the effects of music therapy on children with cancer found that it could help reduce fear and distress while improving family relationships.

A spokesperson for Teenage Cancer Trust said getting children with cancer to co-operate and communicate was most important.

“Every day in UK, around seven young people aged between 13 and 24 are diagnosed with cancer. We know that being treated alongside others their own age makes a huge difference to their whole experience, especially if it’s in an environment that allows young people with cancer to support each other.”

Source: BBC news


Even Light Exercise Has Health Benefits

Light-intensity activities that get you off the couch may be beneficial to your health, even if you don’t work up a sweat, a new study suggests.

People in the study who spent more time moving around than sitting during the day generally had favorable insulin and triglyceride (blood fat) levels, even if they did not do the amount of exercise that national guidelines recommend.

“These findings demonstrate the importance of minimizing sedentary activities, and replacing some of them with light-intensity activities, such as pacing back and forth when on the phone, standing at your desk periodically instead of sitting and having walking meetings instead of sit-down meetings,” study researcher Paul Loprinzi, an assistant professor at Bellarmine University in Louisville, Ky., said in a statement.

Other light activities that can reduce sedentary time include leisurely biking, playing Wii Fit, sitting on a balance ball, playing a musical instrument and gardening.

Although these light exercises may not be as beneficial to your health as vigorous activities are, they are still “much better than lying on the couch, watching TV,” said study researcher Bradley Cardinal, co-director of the Sport and Exercise Psychology Program at Oregon State University.

The Centers for Disease Control and Prevention recommends that adults do at least 150 minutes of moderate-intensity aerobic activity (such as brisk walking) per week, or 75 minutes of vigorous activity such as running or swimming laps.

In the study, the researchers analyzed information from more than 5,500 U.S. adults who wore accelerometers to record their movements.

About half of participants engaged in less than 150 minutes of moderate to vigorous activity a week, and spent more time sitting than performing light-intensity activities.

Other recent studies have found that too much time sitting is linked with an increased risk of chronic diseases such as heart disease and type 2 diabetes, as well as breast and colon cancers.

The new study was published online Dec. 25 in the journal Preventive Medicine.

Source: livescience