Radiation treatment of eye cancers using iodine-125

Generally, public believe that scientific and technological developments in the field of nuclear energy in India are mostly confined to the strategic area and to nuclear power generation. Medical, industrial and research uses of ionising radiation, which rose manifold over the past few decades have not got due recognition.

Radiation treatment of eye cancers using iodine-125

At any moment, hospitals in many parts of the country are carrying out radiation treatment in one form or other on many thousands of cancer patients. BARC-made ‘BARC I-125 Ocu-Prosta seed’ is an ideal choice to treat retinoblastoma and uveal tract melanoma, two forms of rare eye cancers.

Unlike conventional treatment which involves removal of eyes with the tumour to save the patient, successful radiation treatment saves the eye and retains vision.

Since iodine -125 ( I-125) has a half life of about 60 days, scientists have enough time to transport the sources from its production site at BARC laboratories to the treatment centres at different parts of the country. Half life is the period in which radioactivity of a source reduces to half its original value.

Modelling the eye

Specialists model the affected eye of each patient by using computerised tomography (CT) or magnetic resonance imaging (MRI) procedures. They identify the orientation of tumour borders relative to the surrounding healthy structures such as the optic nerve, centre of the eye etc by using ultrasound.

Using the imaging data in a dedicated software programme, they arrive at the number of radioactive seeds, their activity and their placement on the plaque to produce the ideal dose distribution.

Physicians use this information to fix appropriate number of I-125 seeds on a plaque of suitable size using a tissue compatible auto-polymerising glue. By accurately positioning the plaque, they restrict irradiation to the tissue where it is needed.

I-125 which emits low energy gamma rays helps to spare healthy tissues; it reduces side effects and related morbidity. Generally, physicians carry out the treatment in 5 to 10 consecutive days. BARC scientists have independently measured the dose distribution around I-125 seeds.

It was truly a multidisciplinary programme. Radiopharmaceuticals Division, Laser Processing and Advanced Welding Section, Centre for Design and Manufacture, Radio metallurgy Division, Radiological Physics and Advisory Division and external agencies such as Hindustan Machine Tools Limited, Bangalore and Titan Industries Limited, Hosur, collaborated in many areas to prepare the seeds.

Batch process

BARC scientists produce Iodine 125 in a batch process by irradiating 4 gramme of xenon-124 gas in the Dhruva reactor for a period of 15 days. Xenon -125 produced by the neutron interaction decays into I-125.

After removing from the reactor, they keep each sample for 50 days to ensure that I-126, an unwanted radioisotope which is also produced during neutron irradiation decays to negligible values.

“The need for technically intense operations in the handling of gaseous targets in hostile radiation environments, the transformation of I-125 into a chemical form within acceptable radionuclide impurities, and adherence to radioactive concentrations of the final I-125 solution are some of the key technical challenges during the production of I-125,” BARC scientists wrote in Industrial & Engineering Chemistry Research (2012, 51, 8575-8582), a journal of the American Chemical Society. This paper vividly describes the marvellous engineering and design procedures and production processes.

BARC-produced I-125 seeds are available in 50 micrometre thick titanium (titanium is bio-compatible) capsules of diameter 0.8mm and length 4.75 mm. Scientists subject these tiny seeds to a variety of tests mandated by the Atomic Energy Regulatory Board to ensure safety.

In September 2003, BARC supplied the first batch of I-125 seeds to Sankara Nethralaya to treat a four-year-old child suffering from retinoblastoma.

As on May 31, 2014, BARC supplied 1124 seeds to treat 95 patients from India and neighbouring countries. Sankara Nethralaya, Chennai, PD Hinduja National Hospital, Shri Ramakrishna Institute of Oncology Research/Arvind Eye Hospital, Coimbatore are collaborating in the programme

The patients treated so far are too few to estimate cure rates, eye salvation rates etc, though some preliminary results amply demonstrate the potential value of this treatment modality.

I-125 seeds are also useful in treating prostate cancer. BARC supplied so far 370 I-125 seeds to PD Hinduja Hospital, Mumbai to treat five patients. For treating prostate cancer, physicians implant I-125 seeds permanently in patients.

BARC’s achievement

In spite of extensive demand for I-125 seeds worldwide, only a few companies produce I-125 seeds, as the manufacturing processes are too complicated. BARC has developed the technology from scratch. The Board of Radiation and Isotope Technology (BRIT) has plans to produce I-125 seeds commercially. It has great potential for internal use and hopefully for export.

Source: The Hindu


Normal-Weight Teens Can Have Eating Disorders

Teenagers do not need to be rail thin to be practicing the dangerous eating behaviors associated with anorexia, a new study suggests.

Normal-Weight Teens Can Have Eating Disorders

Rather, the true measure of trouble may be significant weight loss, and the Australian researchers noted that a drastic drop in weight carries the same risk for life-threatening medical problems even if the patient is a normal weight.

Even more concerning, the scientists saw a nearly sixfold increase in this type of patient during the six-year study period.

Anorexia nervosa is a mental illness characterized by excessive weight loss and psychological symptoms that include a distorted self-image and fear of weight gain. In some patients, this can also include depression and anxiety. Those who have these symptoms but are not underweight enough to qualify for the definition of anorexia fall under a different diagnosis, known as Eating Disorder Not Otherwise Specified (EDNOS-Wt).

“Emaciated bodies are the typical image portrayed in the media of patients with restricting eating disorders such as anorexia nervosa,” said lead researcher Melissa Whitelaw, a clinical specialist dietitian at The Royal Children’s Hospital in Melbourne, Australia. “This paper highlights that it is not so much about the weight but the weight loss that can lead to a serious eating disorder. The complications of malnutrition can occur at any weight.”

In her study, which included 99 teens aged 12 to 19, Whitelaw found only 8 percent of the patients had EDNOS-Wt in 2005, but more than 47 percent of the patients had it in 2009.

“I was surprised to see how much it increased,” Whitelaw said. “I was also surprised at how similar they were not only physically but also psychologically. Everything about them was anorexia except that they don’t look really skinny.” Both groups had even lost a similar amount of weight: a median 28 pounds for those with anorexia and 29 pounds for those with EDNOS-Wt.

Other experts noted that it can be difficult to spot this less obvious eating disorder.

“We are conditioned to think that the key feature of anorexia nervosa is low body mass index [BMI],” said Cynthia Bulik, director of the Center of Excellence for Eating Disorders at the University of North Carolina at Chapel Hill. BMI measures whether a person is a healthy weight for their height.

“In fact, we miss a lot of eating disorders when focusing primarily on weight,” Bulik added.

Leslie Sim, an assistant professor of psychology at Mayo Clinic Children’s Center in Rochester, Minn., said, “People are calling it atypical anorexia, but we see it every day. We see people who have all the psychological, behavioral, cognitive and physical symptoms of anorexia nervosa, but the only difference is their weight.”

Source: web md


First Human Trials of Ebola Vaccine to Start

The U.S. government and drugmaker GlaxoSmithKline will announce Thursday that they are starting the first human trials of a vaccine against the deadly Ebola virus.

First Human Trials of Ebola Vaccine to Start

The National Institutes of Health will sponsor the first trial of the vaccine, one of several being developed against Ebola. It’s fast-tracked the testing because of the outbreak of Ebola that is ravaging three West African countries.

Ebola has killed more than 1,400 people out of 2,600 infected in Liberia, West Africa and Guinea in the ongoing outbreak, by far the worst outbreak of Ebola ever seen. And the World Health Organization says those numbers almost certainly understate the true numbers of those infected and killed.

The National Institute of Allergy and Infectious Diseases, part of the NIH, has been working on an Ebola vaccine for years. The idea was to develop it to defend people in case Ebola was ever used in a biological attack. Previous outbreaks of the virus were always too small and too easily controlled to justify developing a vaccine quickly.

NIAID was working with a small Swiss-Italian biotech company called Okairos to develop the vaccine. It’s been shown to protect monkeys against Ebola.

Glaxo bought the company last year. The next step is to test the vaccine in people, both to see if it’s safe and to see if it stimulates the immune system in a way that would be predicted to protect people from infection.

The vaccine is made using a virus called an adenovirus that infects chimpanzees but not people. The virus is genetically engineered with a single piece of Ebola virus, a protein that the immune system can recognize, but which doesn’t make people sick.

Several other companies are working to develop Ebola vaccines, including Crucell, a small biotech called Profectus Biosciences, Iowa-based NewLink Genetics and Immunovaccine Inc, based in Nova Scotia, Canada.

Two American medical missionaries, Dr. Kent Brantly and Nancy Writebol, were treated with an experimental therapy made by California-based Mapp Biopharmaceutical. Three Liberian doctors also received the drug. One died and the other two have recovered.

Source: nbc news


Health Benefits of Corn

Health benefits of corn include controlling diabetes, prevention of heart ailments, lowering hypertension and prevention of neural-tube defects at birth. Corn or maize is one of the most popular cereals in the world and forms the staple food in many countries, including the United States and many African countries.

Health Benefits of Corn

The kernels of corn are what hold the majority of corn’s nutrients, and are the most commonly consumed parts of the vegetable. The kernels can come in multiple colors, depending on where the corn is grown and what species or variety they happen to be. Another genetic variant, called sweetcorn, has more sugar and less starch in the nutritive material.

Nutritional Value of Corn

Corn not only provides the necessary calories for healthy, daily metabolism, but is also a rich source of vitamins A, B, E and many minerals. Its high fiber content ensures that it plays a significant role in the prevention of digestive ailments like constipation and hemorrhoids as well as colorectal cancer. The antioxidants present in corn also act as anti-carcinogenic agents and prevent Alzheimer’s disease.

Health Benefits of Corn

Corn provides many health benefits due to the presence of quality nutrients within. Besides being a delicious addition to any meal, it is also rich in phytochemicals, and it provides protection against a number of chronic diseases. Some of the well-researched and widespread health benefits of corn are listed below.Rich source of calories: Corn is a rich source of calories and is a staple among dietary habits in many populations. The calorific content of corn is 342 calories per 100 grams, which is among the highest for cereals. It is why corn is often turned to for quick weight gain, and combined with the ease and flexibility of growing conditions for corn, the high calorie content makes it vital for the survival of dozens of agricultural-based nations.

Reduces risk of hemorrhoids and colorectal cancer: The fiber content of one cup of corn amounts to 18.4% of the daily recommended amount. This aids in alleviating digestive problems such as constipation and hemorrhoids, as well as lowering the risk of colon cancer due to corn being a whole-grain. Fiber has long been promoted as a way to reduce colon risk, but insufficient and conflicting data exists for fiber’s relationship with preventing cancer, although whole-grain consumption, on the whole, has been proven to reduce that risk. Fiber helps to bulk up bowel movements, which stimulates peristaltic motion and even stimulates the production of gastric juice and bile. It can also add bulk to overly loose stools, which can slow reduce the chances of Irritable Bowel Syndrome (IBS) and diarrhea.

Rich source of vitamins: Corn is rich in vitamin B constituents, especially Thiamin and Niacin. Thiamin is essential for maintaining nerve health and cognitive function. Niacin deficiency leads to Pellagra; a disease characterized by diarrhea, dementia and dermatitis that is commonly observed in malnourished individuals. Corn is also a good source of Pantothenic acid, which is an essential vitamin for carbohydrate, protein, and lipid metabolism in the body. Deficiency of folic acid in pregnant women can lead to the birth of underweight infants and may also result in neural tube defects in newborns. Corn provides a large percentage of the daily folate requirement, while the kernels of corn are rich in vitamin E, a natural antioxidant that is essential for growth and protection of the body from illness and disease.

Provides necessary minerals: Corn contains abundant minerals which positively benefit the bodies in a number of ways. phosphorous, along with magnesium, manganese, zinc, iron and copper are found in all varieties of corn. It also contains trace minerals like selenium, which are difficult to find in most normal diets. Phosphorous is essential for regulating normal growth, bone health and optimal kidney functioning. Magnesium is necessary for maintaining a normal heart rate and for increasing bone strength.

Antioxidant properties: According to studies carried out at Cornell University, corn is a rich source of antioxidants which fight cancer-causing free radicals. In fact, unlike many other foods, cooking actually increases the amount of usable antioxidants in sweet corn. Corn is a rich source of a phenolic compound called ferulic acid, an anti-carcinogenic agent that has been shown to be effective in fighting the tumors which lead to breast cancer as well as liver cancer. Anthocyanins, found in purple corn, also act as scavengers and eliminators of cancer-causing free radicals. Antioxidants have been shown to reduce many of the most dangerous forms of cancer because of their ability to induce apoptosis in cancerous cells, while leaving healthy cells unaffected. This is particularly relevant when phytochemicals are the source of the antioxidants, which is another type of chemical found in high volumes in corn.

Protecting Your Heart: According to researchers, corn oil has been shown to have an anti-atherogenic effect on cholesterol levels, thus reducing the risk of various cardiovascular diseases. Corn oil, particularly, is the best way to increase heart health, and this is derived from the fact that corn is close to an optimal fatty acid combination. This allows omega-3 fatty acids to strip away the damaging “bad” cholesterol and replace them at the binding sites. This will reduce the chances of arteries becoming clogged, will reduce blood pressure, and decrease the change of heart attack and stroke.

Prevents Anemia: The vitamin B12 and folic acid present in corn prevent anemia caused by a deficiency of these vitamins. Corn also has a significant level of iron, which is one of the essential minerals needed to form new red blood cells; a deficiency in iron is one of the main cause of anemia as well.

Lowers LDL Cholesterol: According to the Journal of Nutritional Biochemistry, consumption of corn husk oil lowers plasma LDL cholesterol by reducing cholesterol absorption in the body. As mentioned earlier, this reduction of LDL cholesterol does not mean a reduction in HDL cholesterol, which is considered “good cholesterol” and can have a variety of beneficial effects on the body, including the reduction of heart disease, prevention of atherosclerosis, and a general scavenger of free radicals throughout the body.

Vitamin-A Content: Yellow corn is a rich source of beta-carotene, which forms vitamin A in the body and is essential for the maintenance of good vision and skin. Beta-carotene is a great source of vitamin-A because it is converted within the body, but only in the amounts that the body requires. Vitamin-A can be toxic if too much is consumed, so deriving vitamin-A through beta-carotene transformation is ideal. Vitamin-A will also benefit the health of skin and mucus membranes, as well as boosting the immune system.

The amount of beta-carotene in the body that is not converted into vitamin-A acts as a very strong antioxidant, like all carotenoids, and can combat terrible diseases like cancer and heart disease. That being said, smokers need to be careful about their beta-carotene content, because smokers with high beta-carotene levels are more likely to contract lung cancer, while non-smokers with high beta-carotene content are less likely to contract lung cancer.

Controls diabetes and hypertension: In recent decades, the world has seemed to suffer from an epidemic of diabetes. Although the exact mechanism for this cannot be pinpointed, it is generally assumed to relate to nutrition. Eating more organic fruits and vegetables, like corn, has been thought to be a return to an older style of diet, and it has been linked to reduced signs of diabetes. Studies have shown that the consumption of corn kernels assists in the management of non-insulin dependent diabetes mellitus (NIDDM) and is effective against hypertension due to the presence of phenolic phytochemicals in whole corn. Phytochemicals can regulate the absorption and release of insulin in the body, which can reduce the chance of spikes and drops for diabetic patients and help them maintain a more normal lifestyle.

Cosmetic benefits: Corn starch is used in the manufacturing of many cosmetic products and may also be applied topically to soothe skin rashes and irritation. Corn products can be used to replace carcinogenic petroleum products which are major components of many cosmetic preparations. Many of the traditional skin creams contain petroleum jelly as a base material, which can often block pores and make skin conditions even worse.

Source: organic facts


Ebola spreads to Nigeria oil hub Port Harcourt

Nigeria has confirmed its first Ebola death outside Lagos – a doctor in the oil hub of Port Harcourt. A further 70 people are under surveillance in the city, while his wife has been put under quarantine.

Ebola spreads to Nigeria oil hub Port Harcourt

He died last Friday but the results of the tests have only just been announced by Nigeria’s health minister. The latest figures show that more than 1,550 people have died, with more than 3,000 confirmed cases – mostly in Guinea, Liberia and Sierra Leone.

West Africa’s health ministers are meeting in Ghana to discuss how to tackle the world’s most deadly Ebola outbreak.  Ebola Virus Disease (EVD)

  • Symptoms include high fever, bleeding and central nervous system damage
  • Fatality rate can reach 90% – but current outbreak has mortality rate of about 55%
  • Incubation period is two to 21 days
  • There is no vaccine or cure
  • Supportive care such as rehydrating patients who have diarrhoea and vomiting can help recovery

Fruit bats, a delicacy for some West Africans, are considered to be virus’s natural hostEbola was taken to Nigeria by Patrick Sawyer, a Liberian-American man who travelled to Lagos before dying. One of his contacts evaded Nigeria’s surveillance team and travelled to Port Harcourt, where he sought medical treatment, Health minister Onyebuchi Chukwu said.

Although the man later recovered, the doctor who treated him died and tests showed he had Ebola, the minister said. The doctor who treated Mr Sawyer also died.

More than 240 health workers have been infected with Ebola – a rate which the World Health Organization (WHO) said was “unprecedented”. It noted that in many cases protective suits, even rubber gloves and face masks, were not available.

The doctor becomes the sixth fatality in Nigeria, which is Africa’s most populous country. On Wednesday, Nigeria announced that schools would not reopen until 13 October in order to try and contain the disease.

Source: bbc news


The Toothpaste Ingredient That Has Experts Worried

How safe is your toothpaste? A flurry of recent news stories about Colgate Total Toothpaste and triclosan, a chemical with a somewhat checkered past, may have you wondering.

The Toothpaste Ingredient That Has Experts Worried

Triclosan is best known as an ingredient in antibacterial soaps that doesn’t seem to offer any extra germ-killing benefits, while possibly promoting drug-resistant bacteria in the environment. In fact, the Food and Drug Administration said in December that there was no evidence that triclosan-containing products are more effective than plain soap and water.

Colgate-Palmolive removed triclosan from Palmolive dish detergent and Softsoap hand soap back in 2011, according to Bloomberg News, but not their Total Toothpaste. They say it prevents gingivitis or early gum disease better than other brands, precisely because it contains triclosan. The FDA reviewed the data in 1997 and says “…the evidence showed that triclosan in this product was effective in preventing gingivitis.”

So what’s the big deal? The issue is that there are lingering concerns about triclosan’s safety in general, not just as a problem in the environment. And those concerns are based on studies in the animals, which don’t always translate easily to human risk

“A concern specific to triclosan is its potential to act as an ‘endocrine disruptor,’ which means that it can bind to hormone receptors and interfere with normal hormonal function, including thyroid and reproductive hormones,” says Joshua U. Klein, MD assistant clinical professor of obstetrics, gynecology and reproductive medicine at Mount Sinai School of Medicine in New York City.

However, the concentrations of triclosan researchers are feeding lab animals are “several levels higher than what humans would be exposed to,” says Jessica Savage, MD, a physician with Brigham & Women’s Hospital and a researcher with the Harvard School of Public Health’s NIEHS Center for Environmental Health, where she is conducting research on possible connections between triclosan and allergies.

And these animals are actually injected with or fed the triclosan, while humans absorb small amounts through their skin or from brushing their teeth.

“We’re exposed to very little of this product,” Dr. Savage notes. “Especially when you’re brushing your teeth, you’re spitting [the toothpaste] out.”

The FDA says triclosan is not known to be hazardous to humans, and considers it safe in products—just not effective at killing germs any better than soap. “There’s some animal data but I don’t think there’s human data that suggests a causal relationship between triclosan and adverse health outcomes,” says Dr. Savage. Even though she studies triclosan and allergies, she hasn’t yet found a link. “I’m not near saying triclosan causes allergies,” she adds. “I think we need more good data.”

Dr. Klein doesn’t recommend avoiding triclosan in toothpaste. However couples “focused on fertility and trying to eliminate any possible negative exposure might consider choosing alternative products that do not contain triclosan until further convincing studies are completed in humans,” he says. People concerned about fertility should bear in mind that good oral hygiene may actually increase (or at least preserve) the odds of starting a family. “There are several studies linking reduced inflammation and good oral health to reproductive health so this is significant to fertility in particular,” says Dr. Klein.

For now, the evidence suggests that triclosan may be a bigger threat to the environment than to individuals.

“The issue with triclosan and triclocarban [a related chemical] is not so much that they present a direct threat to human health in concentrations that are found in toothpaste [and other consumer products],” says Robert Lawrence, MD, director of the Center for a Livable Future at the Johns Hopkins Bloomberg School of Public Health. “It’s their long-term accumulation in the environment and their impact on the ecosystem that is most alarming.”

Source: TIME


‘Ban E-cigarette use indoors,’ says WHO

The World Health Organization says there should be a ban on the use of e-cigarettes indoors and that sales to children should stop. In a report the health body says there must be no more claims that the devices can help smokers quit – until there is firm evidence to support this.

WHO experts warn the products might pose a threat to adolescents and the foetuses of pregnant women. But campaigners say regulations must be proportionate.

'Ban E-cigarette use indoors,' says WHO

Tempting flavours
According to the WHO legal steps need to be taken to end the use of e-cigarettes indoors – both in public spaces and in work places. And the report focuses on the potential for products to spark wider cigarette use in children. The health experts call for a ban on advertisements that could encourage children and non-smokers to use the devices.

And they say fruit, candy or alcoholic-drink style flavours should be prohibited too, while the sales of electronic cigarettes from vending machines should be heavily restricted.

1. On some e-cigarettes, inhalation activates the battery-powered atomiser. Other types are manually switched on

2. A heating coil inside the atomiser heats liquid nicotine contained in a cartridge

3. Liquid nicotine becomes vapour and is inhaled. The ‘smoke’ produced is largely water vapour. Many e-cigarettes have an LED light as a cosmetic feature to simulate traditional cigarette glow.

‘Health threats’
The WHO warns exhaled e-cigarette vapour could increase the background air levels of some toxicants and nicotine. According to the team while e-cigarettes are likely to be less harmful than traditional cigarettes, they may pose threats to adolescents and the foetuses of pregnant women who use these devices.

But some researchers suggest tough regulations may prevent smokers having access to products that are potentially less harmful than conventional cigarettes. A spokesman for the British American Tobacco company said: “We have always said that given nicotine is addictive, minimum age laws of 18 for the sale of e-cigarettes should be introduced.

“However, if overly restrictive regulations are introduced hampering innovation or adult usage, then this could simply stifle the growth of new products and prevent smokers from being aware of and having access to them – this can only be bad thing for public health.”

‘Proportionate regulation’
Hazel Cheeseman, at the charity Action on Smoking and Health, said there was no evidence of any harm to bystanders and warned regulation needed to be proportionate.

She added: “Smoking kills 100,000 people in the UK alone. “Smokers who switch to using electronic cigarettes in whole or in part are likely to substantially reduce their health risks.

“Although we cannot be sure that electronic cigarettes are completely safe, as the WHO acknowledges, they are considerably less harmful than smoking tobacco and research suggests that they are already helping smokers to quit.”

Global guidelines
A UK Department of Health spokeswoman said: “More and more people are using e-cigarettes and we want to make sure they are properly regulated so we can be sure of their safety.

“We have already set out our intention to change the law to ban the sale of e-cigarettes to children under 18. “The UK has an existing licensing system for higher strength products and those that claim to help people quit.

“We are also bringing in new European rules to cover lower strength products which will ban most advertising, limit nicotine levels and set standards for ingredients, labelling and packaging.” The WHO’s recommendations were published ahead of a meeting involving all countries that have signed up to an international convention on tobacco control.

New global guidelines could be agreed during the October meeting.

Source: bbc news


Addicted to your phone? You could be suffering from Nomophobia!

The urge to log onto to social networking sites or constantly check email can be a stronger compulsion than the desire to take drugs or drink alcohol.

The combination of Facebook and internet-connected smartphones can be highly addictive, outstripping even addictive drugs such as alcohol and tobacco, according to IT industry research.

Addicted to your phone You could be suffering from Nomophobia

In addition to smartphones’ alleged addictive qualities, too much screen time can also cause mental and physical health problems. Aside from well-documented everyday conditions such as “text neck and “iPad shoulder”, there are more serious consequences of the IT industry’s having fulfilled its 20-year old promise of delivering anything, anywhere, anytime.

Shin Dong-won, professor of psychiatry at South Korea’s Kangbuk Samsung Hospital, says the stimulation from smartphones doesn’t go through the frontal brain lobe, which processes information, but induces direct mental and physical reactions. He therefore believes that smartphones can interfere with children’s normal development during a time when they should be learning patience.

Despite consistent denials from mobile phone makers, there is also a growing list of other health risks associated with increased smartphone usage, including a potential increase in cancer caused by low but rising levels of radiation generated by smartphones and the wireless networks fuelling them.

In 2011, the International Agency for Research on Cancer, classified mobile phone radiation as possibly carcinogenic and recommend additional research into the long-term, heavy use of mobile phones. According to The Ecologist magazine, studies also suggest that our increasing addiction to smartphones may also be causing long-term ecological damage. For example, a Colorado researcher Katie Haggerty planted test plots of aspen seeds and shielded some from the RF radiation from a nearby town’s mobile phone masts. The difference, recorded by the International Journal of Forestry Research, was that those seeds protected from the RF radiation grew into healthy saplings while the exposed plants were small, lacked pigments, and had sickly leaves.

The Ecologist also reports that in Switzerland, the University of Zurich’s Michael Hässig recorded multiple cataracts in calves near mobile phone masts, while a Belgian researcher Joris Everaert of the Research Institute for Nature and Forest (INBO) mapped striking declines in house sparrows in mobile phone masts’ main fields.

But while the IT industry jury may still be out on the long-term health and environmental consequences of such a new technology, there is little doubt we may be spending too much of our time hooked up to it. Last year, a team headed by Wilhelm Hofmann, a behavioural psychologist at Chicago University’s Booth Business School, published the results of an experiment, using BlackBerry smartphones, once named “CrackBerry” phones because of their alleged addictive properties, to gauge the willpower of 205 people aged between 18 and 85 in and around the German city of Wurtzburg.

The study found that, aside from sleep and sex, the urge to log into social networking sites is stronger than any other, including drugs and alcohol. The study found that while a compulsion for logging onto Facebook appears to be less physically harmful than, say cigarettes or alcohol, it still becomes an addiction that “steals” many people’s time.

Mobile phone addiction now has a name “nomophobia”. The first treatment and a facility for dealing with the condition in southern California, the Morningside Recovery Center in Newport Beach, has opened its doors to self-confessed mobile phone addicts. Doctors believe that needing “anything” to feel at ease or normal is technically a disability. The symptoms of nomophobia are generally recognised to include an inability to ever turn the phone off, obsessive checking for missed calls, emails and constantly topping up the power-hungry smartphone battery.

According to research from the United Kingdom-based mobile phone security company SecurEnvoy, 77 per cent of 18-24-year-olds suffer from nomophobia. The study showed that people on average check their phone 34 times a day, and 75 per cent take the phone to the bathroom. SecurEnvoy’s first study, conducted four years ago, revealed that 53 per cent of people suffered from nomophobia. Earlier research in the United States among smartphone users in their late teens and twenties revealed that smartphones and iPads produce roughly the same withdrawal symptoms as addictive drugs such as heroin.

“Addiction has a compulsive aspect that drives it, if you can break the compulsion (I have to respond ‘Right now!’) you can generally control addiction … Voluntarily walking away from the technology regularly reinforces that nothing bad will happen if you do,” says the Silicon Valley analyst Rob Enderle.

But he adds that there is little prospect of mobile internet usage declining in the foreseeable future.

“We are creatures of habit and these habits are being deeply set through repetition. If these services improve their reward structures … we will be even more tightly tied to them,” says Mr Enderle.

Source: beperkde starling

 


Medical marijuana laws may reduce painkiller overdoses

States that have legalized marijuana for managing chronic pain have significantly fewer deaths from prescription painkiller overdoses each year, according to a new study published Monday in JAMA Internal Medicine.

Medical marijuana laws may reduce painkiller overdoses

Researchers looked at medical marijuana laws and death certificate data in all 50 states between 1999 and 2010. During that time, just 13 states had medical marijuana laws in place.

“We found there was about a 25% lower rate of prescription painkiller overdose deaths on average after implementation of a medical marijuana law,” lead study author Dr. Marcus Bachhuber said.

In 2010 alone, he said, states with medical marijuana laws had approximately 1,700 fewer overdose deaths than would have been expected based on the numbers before such laws were passed.

Bachhuber, a primary care doctor at the Philadelphia Veterans Affairs Medical Center, has treated many chronic pain patients.

“It can be challenging for people to control chronic pain, so I think the more options we have the better,” he said. “But I think it’s important, of course, to weigh the risks and benefits of medical marijuana.”

Opioid analgesics are a class of drug that includes painkillers like morphine, oxycodone and methadone. According to the study, the number of patients in the United States with chronic pain who get prescriptions for one of these drugs has nearly doubled over the last 10 years, and overdose rates have risen dramatically.

Statistics from the Centers for Disease Control and Prevention tell the story of a problem they say is now an epidemic: Deaths from drug overdose have been rising steadily over the past two decades and have become the leading cause of injury death in the United States. In 2011, 55% of drug overdose deaths were related to prescription medications; 75% of those involved opioid analgesics.

“Prescription drug abuse and deaths due to overdose have emerged as national public health crises,” said Colleen Barry, a senior author on the study and associate professor at Johns Hopkins Bloomberg School of Public Health. “As our awareness of the addiction and overdose risks … grows, individuals with chronic pain and their medical providers may be opting to treat pain entirely or in part with medical marijuana.”

Twenty-three states and the District of Columbia currently have medical marijuana laws on the books. They address a gamut of conditions — from cancer, HIV, multiple sclerosis to glaucoma — where cannabis provides relief. In most states, chronic or severe pain is the primary reason.

According to the American Academy of Pain Medicine, more than 1.5 billion people worldwide suffer from chronic pain, including 100 million Americans.

The academy’s website describes chronic pain this way: “Chronic pain persists. Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial mishap — sprained back, serious infection, or there may be an ongoing cause of pain — arthritis, cancer, ear infection, but some people suffer chronic pain in the absence of any past injury or evidence of body damage.”

Dr. Lynn Webster, a past president of the academy, said he’s not surprised by the study results or that marijuana might be a safer alternative to opioids for some people.

“AAPM believes that we need to do research on cannabinoids to determine its safety and efficacy,” he said. “The problem with medical marijuana is that we never know using marijuana what chemicals are being ingested. That makes it really unpredictable, but the use of cannabinoids may well have a place in the treatment of pain and other diseases. The AAPM believes that the DEA should reschedule cannabinoids from Schedule I to Schedule II so that it will make it easier for research to be conducted.”

The researchers of this latest study said the link between medical marijuana laws and overdose deaths is not completely clear. There were some limitations to the study. For example, death certificates may not classify overdose deaths correctly and opioid analgesics reporting on these certificates may differ state-to-state.

Bachhuber said more research is needed before any recommendations can be made. “We can’t know directly the underlying mechanism of our findings, but based on what we know, we think it could be due to safer treatment of chronic pain,” Bachhuber said. “We found that medical marijuana laws might provide unexpected benefits to public health. As more states pass these laws, it will be important to continue collecting information to see if what we found may be happening in other states as well.”

Source: cnn


Improper nutrition linked to oral health problems

Today, taking care of teeth is about more than going to the dentist every six months. In fact, what a person eats outside of those two visits is essential for oral and overall health.

Improper nutrition linked to oral health problems

According to the Academy of Nutrition and Dietetics, “. . . nutrition is an integral component of oral health” and “collaboration between dietetics practitioners and oral health care professionals is recommended for oral health promotion and disease prevention and intervention.”

Oral health problems that can occur with improper nutrition

While the Academy of Nutrition and Dietetics stresses that the most common chronic oral health condition is the development of cavities, they also note that tooth loss caused by periodontal disease is a serious concern.

Both tooth decay and periodontal disease can be caused by a variety of factors including poor at-home oral hygiene habits, infrequent dental visits, certain medications and smoking. Regarding diet, it’s no secret that consumption of sugary foods plays a role since they leave a sticky residue that can erode teeth.

Even stress, which can be kept at bay with the help of a balanced diet, can contribute to oral health problems. When stressed, a person often grinds and clenches teeth, which can produce wear over time.

Finally, jaw development can change based on diet. One study by the University of Kent showed a correlation between types of foods consumed and the chewing habits required to ingest those foods. The findings showed that the lower jaw specifically grew too short with a “soft” diet, demonstrating an association between societal shifts regarding reliance on wild plants and foods compared to today’s reliance on domesticated choices. Today’s modern foods typically consist of more traditional, softer junk food diets: think of ground up burgers and soft donuts and the finding makes sense.

Best foods and vitamins to keep oral and overall health in shape

The Academy of Nutrition and Dietetics recommends “Eating a healthy balanced diet of fruits, vegetables, lean protein and low-fat dairy products and whole grains that provide essential nutrients for optimum oral health and overall health.”

Some fruits and vegetables include oranges and strawberries since their vitamin C helps fight gum inflammation. Raisins and cranberries have polyphenols that have been shown to keep plaque from sticking to teeth.

Non-soft foods such as celery and carrots are also important. Christine D. Wu, pediatric dental researcher from the University of Illinois, says that “Things like carrots and apples aren’t only loaded with antioxidants, they can help mechanically clean your teeth” by breaking up plaque.

Also, when pregnant, know that a baby’s teeth start to develop as soon as the fifth week of pregnancy. Its suggested that a pregnant mother consume vitamins A, C, D, protein, calcium and phosphorous.

Source: natural news