Rare surgery saves newborn girl

rare surgery2

A baby girl, who was diagnosed with a life threatening congenital heart disease in the womb, got a new lease of life as doctors at a city hospital performed a corrective surgery on her two hours after she was born.

Doctors at Care Hospital said the girl was suffering from a rare disorder wherein the oxygen-rich blood returned from the pulmonary veins was abnormally getting diverted to the liver instead of heart.

“A foetus is dependent on mother’s blood and hence the baby was normal in the womb. But after birth, babies suffering from this rare malformation, referred as Total Anomalous Pulmonary Venous Return (TAPVR), die without a reconstructive surgery,” said Dr K Nageshwar Rao, paediatric cardiologist, Care Hospital, and part of the team that performed the first-of-its-kind surgery.

Source: Healcon


World’s Oldest Cancer Arose in a Dog 11,000 Years Ago

One cancer outlived the dog in which it emerged by spreading its abnormal cells on to other dogs during mating. Now, researchers have named this sexually transmitted canine cancer the oldest known line of cancer cells, at 11,000 years old.

This type of contagious cancer is extremely rare. Canine transmissible venereal tumor (CTVT) is one of only two known diseases in which cancerous cells from one animal infect another. The researchers compare CTVT to a millennia-old “parasitic life form.”

“The cancer cells in all the dogs around the world today are derived from the original dog,” said Elizabeth Murchison, a study researcher and cancer geneticist at the Wellcome Trust Sanger Institute and the University of Cambridge, both in the United Kingdom.

By looking at a particular type of mutation in the cancer cells from two dogs, an Aboriginal camp dog from Australia and an American cocker spaniel from Brazil, Murchison and colleagues estimated when this original dog — Patient Zero for the bleeding, ulcerated genital tumor-causing disease — lived. And since the cancer cells still contain genetic material from the original dog, the team was able to extract a few clues to its identity.

The original dog was likely medium to large in size. It showed genetic similarity to an Alaskan malamute or husky, and carried a mix of genetic variations associated with the domestication of dogs. Because one of the dog’s two sex chromosomes had disappeared in the cancerous cells, it was unclear whether this dog was male or female, and researchers have yet to determine in what part of the world it lived.

The other naturally occurring cancer spread by the transfer of cancerous cells is a facial cancer afflicting Tasmanian devils and transmitted they bite each other, and this disease puts the animals at risk for extinction. These cancers are extremely rare, because the immune system usually recognizes and attacks foreign cells.

In the DNA (deoxyribonucleic acid) of the dog cancer cells, researchers found what Murchison speculates is a clue to how this cancer established itself early on. Although the original dog lived about 11,000 years ago, its DNA showed a level of inbreeding similar to that of a modern dog breed, perhaps because it was part of an isolated population. It is possible the genetic similarity among the dogs it first encountered helped the cancer cells avoid recognition by their immune systems, allowing it to become established, Murchison said.

Likewise, the low genetic diversity among Tasmanian devils may have contributed to the emergence of the contagious facial cancer that threatens these animals, Murchison said. No similar cancer afflicts humans. However, some human cancers are associated with infection by viruses or other pathogens. For instance, human papillomavirus (HPV) is responsible for 26,000 cases of cancer annually in the United States, the U.S. Centers for Disease Control and Prevention has reported.

Source: Yahoo news

 


Addicted to Sugar? Here’s How You Can Beat Your Cravings

sugar

A secret weapon that you may like to use in your own personal war against sugar. It stops cravings in their tracks but also deals with mid-afternoon energy slumps. Ready for it? It’s coconut oil.

Take it a tablespoon at a time

Eat it directly after lunch. Or mix it with a little raw cacao powder to make the simplest chocolate snack

It kills sugar cravings, immediately.
How so? Coconut oil is made up of medium-chain fatty acids, or medium chain triglycerides (MCTs). Indeed, coconut oil is nature’s richest source of MCTs. These fatty acids produce a host of health benefits which you can read about here. But here’s the bit I like: your body sends medium-chain fatty acids straight to your liver to use as energy. This means coconut oil is a source of instant energy, much like sugar and other simple carbohydrates. But although both deliver quick energy to your body, unlike the carbohydrates, coconut oil does not produce an insulin spike in your bloodstream. This saves you from a slump, and is really good news for anyone struggling with insulin issues. Like me.

It fills you up, immediately.
After two tablespoons I’m not hungry for about four hours.

And bonus: it helps you lose weight!
Again, it’s the medium-chain fatty acids. Most plant oils are made up of longer chain fat triglycerides (LCTs). LCTs are typically stored in the body as fat; MCTs are transported directly to the liver, promoting “thermogenesis” which increases the body’s metabolism. There are a stack of studies that have shown this to be the case, like this one. This study shows eating two tablespoons of coconut oil with a meal caused body temperature to rise, boosting metabolism. Plus, MCTs are not easily converted into stored triglycerides and cannot be readily used by the body to make larger fat molecules.

Source: huffington post


Consumer Reports: Too many sodas contain potential carcinogen

A chemical found in many sodas may be dangerous to your health, Consumer Reports says. And no, it’s not sugar (this time).

The golden-brown color of many soft drinks comes with a dose of the chemical 4-methylimidazole, or 4-MeI. On U.S. product labels it appears simply as “caramel coloring.”

Those who say the chemical may possibly cause cancer include the World Health Organization’s International Agency for Research on Cancer and the state of California, which now limits manufacturers to 29 micrograms of exposure for the average consumer per day.

Foods exceeding that limit have to carry a warning label that reads: “WARNING: This product contains a chemical known to the State of California to cause cancer.”

But when Consumer Reports purchased sodas in California and had them analyzed by a lab, it found that one 12-ounce serving of Pepsi One or Malta Goya exceeded the levels permitted without a warning label.
Ten other brands tested by the group did meet the California standard, which is estimated to limit the risk of cancer from 4-MeI to one case in every 100,000 lifetimes of daily exposure.

“We are concerned about both the levels of 4-MeI we found in many of the soft drinks tested and the variations observed among brands, especially given the widespread consumption of these types of beverages,” said Dr. Urvashi Rangan, a Consumer Reports toxicologist, in a statement.

“There is no reason why consumers need to be exposed to this avoidable and unnecessary risk that can stem from coloring food and beverages brown.”
The Food and Drug Administration does not set federal limits on 4-MeI in food, and the data gathered by Consumer Reports show that in some cases consumers outside California are drinking a slightly different ingredient. For example, Pepsi One purchased by the group in December in New York contains four times as much 4-MeI as the same product bought that same month in California.

What is clean eating?
Currently the FDA has no reason to believe that 4-Mel poses a health risk to consumers at the levels found in foods with caramel coloring, agency spokeswoman Juli Putnam told CNN in an e-mail. The government agency is testing a variety of food and beverages with the chemical and reviewing safety data to determine if any regulatory action needs to be taken, she said.

Consumers interested in more information on 4-Mel can check out the FDA’s FAQ page.
In a statement to Consumer Reports, PepsiCo Inc. said data indicate that the average person consumes less than one-third a can of diet soda per day; therefore, its product meets the California standard, even if a complete serving exceeds that limit.

In addition to new federal standards, Consumer Reports is calling on the FDA to “require labeling of specific caramel colors in the ingredient lists of food where it is added, so consumers can make informed choices.”

“First and foremost, consumers can rest assured that our industry’s beverages are safe,” the American Beverage Association said in a statement. “Contrary to the conclusions of Consumer Reports, FDA has noted there is no reason at all for any health concerns, a position supported by regulatory agencies around the world.

“However, the companies that make caramel coloring for our members’ soft drinks are now producing it to contain less 4-MeI, and nationwide use of this new caramel coloring is underway.”

Source: CNN


Screen Time Study Finds Education Drop-Off

With children spending more time in front of screens than ever, parents sometimes try to convince themselves that playing Angry Birds teaches physics, or that assembling outfits on a shopping app like Polyvore fires creativity.

According to a study scheduled for release on Friday, however, less than half the time that children age 2 to 10 spend watching or interacting with electronic screens is with what parents consider “educational” material. Most of that time is from watching television, with mobile devices contributing relatively little educational value.

What is more, the study, by the Joan Ganz Cooney Center, a nonprofit research institute affiliated with the Sesame Workshop, the nonprofit producer of “Sesame Street,” shows that as children spend more time with screens as they get older, they spend less time doing educational activities, with 8- to 10-year-olds spending about half the time with educational content that 2- to 4-year-olds do.

Athena Devlin, a professor of women’s and American studies at St. Francis College in Brooklyn and the mother of two children, said that her son, Elias, a kindergartner, still watched quite a bit of public television, including shows like “Wild Kratts” and “Dino Dan,” and that she has been impressed by the detailed facts he learns.

But her daughter, Laura, a fourth grader, prefers shows like “Jessie” on the Disney Channel or “Total Drama Island” on the Cartoon Network, which Professor Devlin sees as the preteen equivalent of her own addiction to “Scandal.”

“I feel like with the educational content of television, the bottom drops out of it after age 5 or 6,” she said. “It’s a bummer, and I’ve looked out for it.”

She said that when playing games, her daughter liked Wizard101, while both children gravitated toward Fruit Ninja or Clumsy Ninja, whose educational value Professor Devlin does not rate highly.

“It would be nice if they could get pleasure out of something that also taught them something,” she said.

According to the survey, 2- to 4-year-olds spent a little over two hours a day on screen, with one hour and 16 minutes of educational time, while 8- to 10-year-olds spent more than two and a half hours a day on screen, but only 42 minutes was considered educational. The survey was based on interviews with 1,577 parents and conducted online from June 28 to July 24 by GfK, a research company.

The survey allowed parents to assess whether a game or program taught social and emotional skills, as well as cognitive learning related to vocabulary, math or science.

The survey said lower-income families reported that their children spent more time with educational programming on screen than middle-income and higher-income families did. Families earning less than $25,000 said 57 percent of their children’s screen time was educational, while families earning $50,000 to $99,000 said it was 38 percent.

Michael H. Levine, the executive director of the Joan Ganz Cooney Center, said that particularly for the most vulnerable children who might falter in their academic careers, “we need to have a better balance in the way these media are used.”

Vicki Rideout, who wrote the report, said that with teachers seizing on digital media as a new way to ignite children’s interest at school, more needed to be done to ensure that out-of-school screen activities were not only educational but of high quality.

“It’s far too easy for the best stuff only to be available for the kids who already have many opportunities,” said Ms. Rideout, “and to flip into content that has the gloss of education on it, without the substance, for the kids who are in need.”

Michael Thornton, a second-grade teacher at Meriwether Lewis Elementary School in Charlottesville, Va., and the father of three children under 6, said parents were increasingly asking him for referrals to educational apps, like Geared and Glass Tower, for teaching math and spatial recognition skills, and Chicktionary, for vocabulary.

But, he acknowledged, “you have to really take your time to search through them.”


Baby heart-disease risk ‘shaped early in pregnancy’

A baby’s development in the womb in the first weeks of life is critical for future heart health, research suggests.

A link between poor growth in the first trimester and early risk factors for heart disease has been identified for the first time.

The study, in the British Medical Journal, adds to evidence that heart risk is set long before adulthood.

Pregnant women should think about their baby’s heart health as well as their own, the British Heart Foundation said.

The evidence comes from a study tracking the health, from early pregnancy onwards, of nearly 2,000 children born in the Dutch city of Rotterdam.

A team at the Erasmus University Medical School examined links between the child’s size at the first scan (10 to 13 weeks) and markers of future cardiovascular health at the age of six (central body fat, high blood pressure, high insulin levels and high cholesterol).

“Impaired first trimester foetal growth is associated with an adverse cardiovascular risk profile in school age children,” they reported in the British Medical Journal.

“Early foetal life may be a critical period for cardiovascular health in later life.”

Low birth weight is known to be linked to an increased risk of heart disease in later life. But the new research suggests not only birth weight but poor growth in the earliest phase of pregnancy may influence cardiovascular disease risk.

“These results suggest that the first trimester of pregnancy may be a critical period for development of offspring cardiovascular risk factors in later life,” study author Prof Vincent Jaddoe told BBC News.

“Therefore adverse maternal lifestyle habits influencing early foetal growth may have persistent consequences for their offspring, many decades later. ”

This was the first study showing this link and replication in other studies was needed, he added.

Critical stage
Amy Thompson, senior cardiac nurse at the British Heart Foundation, said the first few months of pregnancy were a critical stage in a baby’s development.

“This study suggests that foetal growth within this time may influence their heart health later in life,” she said.

“However, as the researchers acknowledge themselves, further studies are needed to understand why this pattern exists and what it might mean for preventing heart disease.

“If you are pregnant, or planning a family, you should be thinking about your baby’s heart health as well as your own,” she added.

“If you smoke, speak to your GP or midwife about quitting, and keep a check on your blood pressure.

“Your midwife will also advise you on other ways you can make healthier choices during pregnancy.”

Source: BBC news


Marriage at 25 or older good for men’s bones

Researchers at UCLA have suggested that marriage is good for the health of men’s bones, but only if they marry when they’re 25 or older.

In a new study, researchers found evidence that men who married when they were younger than 25 had lower bone strength than men who married for the first time at a later age.

In addition, men in stable marriages or marriage-like relationships who had never previously divorced or separated had greater bone strength than men whose previous marriages had fractured, the researchers said. And those in stable relationships also had stronger bones than men who never married.

Although for women there were no similar links between bone health and being married or in a marriage-like relationship, the study authors did find evidence that women with supportive partners had greater bone strength than those whose partners didn’t appreciate them, understand how they felt or were emotionally unsupportive in other ways.

This is the first time that marital histories and marital quality have been linked to bone health, the study’s senior author, Dr. Carolyn Crandall, a professor of medicine in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA, said.

“There is very little known about the influence of social factors – other than socioeconomic factors – on bone health,” Crandall said.

“Good health depends not only on good health behaviors, such as maintaining a healthy diet and not smoking, but also on other social aspects of life, such as marital life stories and quality of relationships,” she said.

The associations between marriage and bone health were evident in the spine but not the hip, possibly due to differences in bone composition, the researchers said.

The data suggested several significant correlations between marriage and bone health – but only for men.

The study authors found that men in long-term stable marriages or marriage-like relationships had higher bone density in the spine than every other male group, including men currently married who had previously been divorced or separated, men not currently in a relationship and men who had never been married.

Among men who first married prior to turning 25, the researchers found a significant reduction in spine bone strength for each year they were married before that age.

For instance, the authors said, those who marry young are likely to be less educated, leading to lower pay and more difficulty in making ends meet.

The study is published online in the peer-reviewed journal Osteoporosis International.

Source: zee news


Blame your genes for your beer bellies

A team of researchers has identified five new genes associated with increased waist-to-hip ratio, potentially moving a step closer to developing a medication to treat obesity or obesity-related diseases.

A person’s measure of belly fat is reflected in the ratio of waist circumference to hip circumference, and it is estimated that genetics account for about 30-60 percent of waist-to-hip ratio (WHR).

The team led by Kira Taylor from University of Louisville School of Public Health and Information Sciences conducted an analysis of more than 57,000 people of European descent, and searched for genes that increase risk of high waist-to-hip ratio, independent of overall obesity.

They investigated over 50,000 genetic variants in 2,000 genes thought to be involved in cardiovascular or metabolic traits.

Their analysis identified three new genes associated with increased WHR in both men and women, and discovered two new genes that appear to affect WHR in women only.

Of the latter, one gene, SHC1, appears to interact with 17 other proteins known to have involvement in obesity, and is highly expressed in fat tissue. In addition, the genetic variant the team discovered in SHC1 is linked to another variant that causes an amino acid change in the protein, possibly changing the function or expression of the protein.

The study was published in journal Human Molecular Genetics.

Source: DNA India


Brisk walk can help beat prostate cancer

Exercise may improve the prognosis of prostate cancer patients by affecting blood vessels in their tumours, a study suggests.

Researchers found that men who walked at a fast pace before being diagnosed with the disease had tumours containing larger and more regularly shaped blood vessels.

Better formed tumour blood vessels may in turn inhibit cancer aggressiveness and promote better responses to treatments, the scientists believe.

Physically active men with prostate cancer have a lower risk of recurrence and death from the disease than those living sedentary lives, but until now the reason has remained a mystery.

The new study looked at 572 prostate cancer patients taking part in a US lifestyle and health investigation called the Health Professionals Follow-up Study.

Men with the fastest walking pace – between 3.3 and five miles per hour – prior to diagnosis had 8 per cent more regularly shaped tumour blood vessels than the slowest walkers who ambled at 1.5 to 2.5 mph.

“Prior research has shown that men with prostate tumours containing more regularly shaped blood vessels have a more favourable prognosis compared with men with prostate tumours containing mostly irregularly shaped blood vessels,” said lead scientist Dr Erin Van Blarigan, from the University of California at San Francisco.

“In this study, we found that men who reported walking at a brisk pace had more regularly shaped blood vessels in their prostate tumors compared with men who reported walking at a less brisk pace.

“Our findings suggest a possible mechanism by which exercise may improve outcomes in men with prostate cancer. Although data from randomised, controlled trials are needed before we can conclude that exercise causes a change in vessel regularity or clinical outcomes in men with prostate cancer, our study supports the growing evidence of the benefits of exercise, such as brisk walking, for men with prostate cancer.”

Dr Matthew Hobbs, deputy director of research at Prostate Cancer UK, said: “Although this research provides a plausible explanation of how exercise might improve outcomes for men with prostate cancer, much more research is needed to confirm the impact of lifestyle factors on men’s recovery.

“We hope that further research in this area may one day give us a way to improve the prognosis for the 40,000 men in the UK who are diagnosed with prostate cancer each year.”

Meanwhile a separate study suggest a good night’s sleep may also held the condition. Scientists have linked higher levels of the night-time hormone melatonin with a 75 per cent reduced risk of advanced disease.

Melatonin is produced in the dark at night. It plays a key role in regulating the body’s sleeping cycle and influences many other functions associated with the body’s 24-hour clock, or circadian rhythm.

Low levels of the hormone are typically associated with disrupted sleep.

Scientists studied 928 Icelandic men who were questioned about their sleep patterns.

Source: the Scotsman


Too much ‘love hormone’ can make healthy people oversensitive

Researchers at Concordia’s Centre for Research in Human Development have shown that too much oxytocin or ” love hormone” in healthy young adults can actually result in over sensitivity to the emotions of others.

With the help of psychology professor Mark Ellenbogen, PhD candidates Christopher Cardoso and Anne-Marie Linnen recruited 82 healthy young adults who showed no signs of schizophrenia, autism or related disorders.

Half of the participants were given measured doses of oxytocin, while the rest were offered a placebo.

The participants then completed an emotion identification accuracy test in which they compared different facial expressions showing various emotional states. As expected, the test subjects who had taken oxytocin saw greater emotional intensity in the faces they were rating.

“For some, typical situations like dinner parties or job interviews can be a source of major social anxiety,” Cardoso, the study’s lead author, said.

“Many psychologists initially thought that oxytocin could be an easy fix in overcoming these worries. Our study proves that the hormone ramps up innate social reasoning skills, resulting in an emotional oversensitivity that can be detrimental in those who don’t have any serious social deficiencies,” he said.

Ultimately, however, oxytocin does have the potential to help people with diagnosed disorders like autism to overcome social deficits.

The study is published in Emotion, a journal of the American Psychological Association.

Source: sisat